摘要
目的 了解广东省新型冠状病毒肺炎的流行病学特征。方法 收集广东省2020年1月19日~2月25日报告的新型冠状病毒肺炎的每日新增确诊病例,对流行病学特征进行描述性分析,人口迁入数据依据百度迁徙规模指数,对日发病率和人口迁入数据开展相关性统计分析。结果 截至2月25日,广东省新型冠状病毒肺炎共报告确诊病例1 347例,累计发病率为1.19/10万,粗病死率0.52%(7/1 347),累计治愈出院人数占比62.44%(841/1 347)。自1月19日报告首例确诊病例后,报告病例数呈快速上升,1月31日当日新增确诊病例127例,达到峰值,之后呈波动下降趋势,2月25日首次出现报告新增确诊病例为0。病例主要集中在珠三角地区,占全省总数的89.98%(1 212/1 347),珠三角地区累计发病率(1.92/10万)高于非珠三角地区(0.27/10万),差异有统计学意义(χ2=647.12,P<0.01),累计发病率最高地区是珠海市(5.18/10万),其次是深圳市(3.20/10万)和广州市(2.32/10万),差异有统计学意义(χ2=55.47,P<0.01)。女性发病率(1.26/10万)高于男性(1.12/10万),差异有统计学意义(χ2=4.97,P<0.05)。广东省日发病率与5天前的人口迁入数据呈正相关关系(相关系数rs= 0.38,t0.05,v=2.03,P<0.05)。结论 广东省新型冠状病毒肺炎疫情得到阶段性控制,但仍需有序控制外来输入人口流动规模,运用现场流行病学调查手段获得更准确全面信息,采用高效敏感的检测排查手段,提高外防输入控制能力。
Abstract
Objective To investigate the epidemical characteristics of Corona Virus Disease 2019 (COVID-19) in Guangdong Province. Methods The daily new confirmed cases of Corona Virus Disease 2019 (COVID-19) in Guangdong Province from January 19 to February 25,2020 were collected for epidemiological descriptive analysis.Spearman rank correlation analysis was conducted with the Baidu migration index and daily incidence in Guangdong Province. Results By February 25,2020,there was 1 347 confirmed case and the cumulative incidence of COVID-19 in Guangdong was 1.19/100,000.There was 7 case died,with a fatality rate of 0.52%(7/1 347),and the cumulative discharged proportion was 62.44%(841/1347).On January 31,2020,there was peaking that 127 new cases were diagnosed,then showing a downward trend of volatility,and on February 25,2020,the new confirmed cases were 0.The cases were mainly concentrated in the Pearl River Delta region,accounting for 89.98 percent of the province (1 212/1 347),and the cumulative incidence in the Pearl River Delta region (192/100,000) was higher than that in the non-Pearl River Delta region (0.27/100,000),with statistically significant differences (χ2=647.12,P<0.01).The incidence was 1.26/100,000 in females and 1.12/100,000 in males,with statistically significant differences (χ2=4.97,P<0.05).The regions with the highest cumulative incidence were Zhuhai (5.18/100,000),followed by Shenzhen (3.20/100,000) and Guangzhou (2.32/100,000),with statistically significant differences (χ2=55.47,P<0.01).There was a positive correlation between daily morbidity and 5-day-before migration index in Guangdong Province (Correlation coefficient rs =0.38,t 0.05,v =2.03,P<0.05). Conclusion The epidemic of the Corona Virus Disease 2019 has been basically controlled in Guangdong province,but control measures still need to be taken,to control the scale of foreign input population flow in an orderly manner,and obtain more accurate and comprehensive information by means of field epidemiological investigation,and adopt efficient and sensitive detection and investigation methods,improve the control ability of external defense input.
关键词
新型冠状病毒肺炎 /
流行特点 /
人口流动指数 /
流行强度 /
新发传染病
Key words
Corona Virus Disease 2019 (COVID-19) /
Epidemiological characteristics /
Population mobility index /
Epidemic strength /
Emerging Infectious Diseases
赖辉兵, 罗立旷.
广东省新型冠状病毒肺炎流行特征初探[J]. 安徽预防医学杂志. 2020, 26(4): 253-257 https://doi.org/10.19837/j.cnki.ahyf.2020.04.003
LAI Huibing, LUO Likuang.
Preliminary analysis on the epidemiological characteristics of Corona Virus Disease 2019 in Guangdong Province[J]. Anhui Journal of Preventive Medicine. 2020, 26(4): 253-257 https://doi.org/10.19837/j.cnki.ahyf.2020.04.003
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参考文献
[1] Li Q,Guan X,WU P,et al.Early transmission dynamics in Wuhan,China,of novel coronavirus-infected pneumonia[J].N Engl J Med,2020,DOI:10.1056/NEJ-Moa2001316.
[2] 国家卫生健康委医政医管局.关于印发新型冠状病毒肺炎诊疗方案(试行第六版)的通知.http://www.nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd94d329df351d7da8aefc2.shtml.
[3] Tan WJ,Zhao X,Ma XJ,et al.A novel coronavirus genome identified in a cluster of pneumonia cases-Wuhan,China 2019-2020[J].China CDC Weekly,2020,2:61-62.
[4] 世卫组织总干事在 2020 年 2 月 11 日举行的 2019 新型冠状病毒新闻通报会上的讲话[R/OL].https://www.who.int/zh/dg/speeches/detail/.
[5] Wang D,Hu B,Hu C,et al.Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan,China[J].JAMA,2020.
[6] 世卫组织总干事2020年2月28日在2019冠状病毒病疫情媒体通报会上的讲话[R/OL]https://www.who.int/zh/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19-28-february-2020.
[7] 世卫组织总干事2020年2月27日在2019冠状病毒病疫情媒体通报会上的讲话[R/OL]https://www.who.int/zh/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---27-february-2020.
[8] 国家卫生健康委疾病预防控制局.国家卫生健康委办公厅关于印发新型冠状病毒肺炎防控方案(第五版)的通知.http://www.nhc.gov.cn/jkj/s3577/202002/a5d6f7b8c48c451c87dba14889b30147.shtml.
[9] 中华预防医学会新型冠状病毒肺炎防控专家组.新型冠状病毒肺炎流行病学特征的最新认识[J/OL].中国病毒病杂志:1-7[2020-02-29].https://doi.org/10.16505/j.2095-0136.2020.0015.
[10] 中国疾病预防控制中心新型冠状病毒肺炎应急响应机制流行病学组.新型冠状病毒肺炎流行病学特征分析[J].中华流行病学杂志,2020,41(2):145-151.
[11] Chan JF,Yuan S,Kok KH,et al.A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission:a study of a family cluster[J].Lancet,2020,395(10223):514-523.
[12] 王宣焯,廖聪慧,李志慧等.广东省新型冠状病毒肺炎早期流行与时空分布情况初步分析[J/OL].热带医学杂志,2020(03):1-8[2020-02-28].http://kns.cnki.net/kcms/detail/44.1503.R.20200213.0806.002.html.