目的 分析安徽省新型冠状病毒肺炎未成年患者的临床及流行病学特征,为新型冠状病毒肺炎疫情防控提供科学依据。方法 根据2020年1月22日至2月21日传染病监测系统中年龄在17岁及以下的新型冠状病毒肺炎病例个案情况和流行病学调查资料,分析病例临床特点和流行病学特征。结果 安徽省共报告47例未成年确诊病例,平均年龄10.2岁;男女性别比为1.47∶1;学生病例有37例;发病高峰期在2月1日至2月6日;61.7%的病例(29/47)来自皖北地区;87.2%的病例(41/47)有确诊病例接触史,多因接触直系/旁系亲属后发病;首发症状主要为发热,占71.9%(23/32),上呼吸道感染症状常见,少见乏力;与成年人病例相比,未成年病例病情较轻。结论 安徽省未成年确诊病例以男性,学生人群居多;多因接触确诊的家庭病例呈现家庭聚集性发病;临床症状较轻。
Abstract
Objective To analyze the clinical and epidemiological characteristics of COVID-19 minor cases in Anhui Province so as to provide scientific basis for epidemic prevention and control. Methods According to the case and epidemiological investigation data of COVID-19 cases aged 17 and below in the infectious disease surveillance system from January 22 to February 21st,2020,the clinical and epidemiological characteristics of the cases were analyzed. Results A total of 47 confirmed cases of minors were reported in Anhui Province,with an average age of 10.2 years.The ratio of male to female was 1.47:1 and 37 cases were students.The peak period of incidence was from February 1 to February 6.61.7% of the cases (29/47) came from northern Anhui; 87.2% of the cases (41/47) had a history of contact with confirmed cases who were their immediate family or collateral branches of the family.The first symptom was mainly fever,accounting for 71.9% (23/32).The symptoms of upper respiratory tract infection were common and fatigue was rare.COVID-19 minor cases had relatively mild symptoms compared to adult cases. Conclusion The COVID-19 confirmed cases of minors in Anhui Province were mainly male and students.Most of these cases had a history of contact with confirmed family cases,showing family aggregation,and their clinical symptoms are mild.
关键词
未成年组 /
安徽 /
新型冠状病毒肺炎 /
临床表现 /
流行病学特征
Key words
Minor group /
Anhui /
COVID-19 /
Clinical manifestation /
Epidemiological characteristics
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参考文献
[1] 中华预防医学会新型冠状病毒肺炎防控专家组.新型冠状病毒肺炎流行病学特征的最新认识[J].中国病毒病杂志,2020,10(2):86-90.
[2] 国家卫生健康委.截至3月11日24时新型冠状病毒肺炎疫情最新情况[A/OL].(2020-03-12)[2021-05-12].http://www.nhc.gov.cn/xcs/yqtb/202003/37c1536b6655473f8c2120ebdc475731.shtm.
[3] 安徽省卫生健康委.3月12日安徽省报告新冠肺炎疫情情况[A/OL].(2020-03-12)[2021-05-12].http://wjw.ah.gov.cn/ztzl/xxgzbdfyyqfk/fkdt/52041911.html.
[4] 马娟,沈蕾蕾,刘慧敏等.儿童新型冠状病毒肺炎流行期间防控建议解读[J].重庆医学,2020,49(17):2816-2819.
[5] 佘佳桐,刘文君.儿童新型冠状病毒(2019-nCoV)肺炎的流行病学特征与防控措施[J].热带医学杂志,2020,20(2):153-155,172.
[6] 杨斌斌,朱月玲.儿童与成人新型冠状病毒肺炎(COVID-19)流行病学与治疗的现状分析[J].西安交通大学学报(医学版),1-10.
[7] 沈辰,王吟.安徽省人口经济压力统计分析[J].合肥师范学院学报,2015,33(3):16-18.
[8] 刘庆宝.城镇化进程中安徽省人口结构问题、影响及对策研究[J].理论建设,2013,(5):5-9.
[9] 樊洋,徐梦琦,丁春燕.安徽流动人口问题及对策[J].云南农业大学学报(社会科学),2018,12(4):38-44.
[10] 庹虎,刘芳,王军陵等.儿童新型冠状病毒感染的临床特征及家庭防控[J].武汉大学学报(医学版),1-5.
[11] 罗小平,华方.要格外重视新冠肺炎中的儿童群体[N].健康报,2020-02-11.
[12] Liang Su,Xiang Ma,Huafeng Yu,et al.The different clinical characteristics of corona virus disease cases between children and their families in China-the character of children with COVID-19[J].Emerg Microbes Infect,2020,9(1):707-713.
[13] HAR A,SNBBC D.The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak[J].J Autoimmun,2020,102433.
[14] LA Rui,SQIA GZA B.Analysis of angiotensin-converting enzyme 2 (ACE2) from different species sheds some light on cross-species receptor usage of a novel coronavirus 2019-nCoV Sciencd Science Direct[J].J Infect,2020,80(4):469-496.
[15] Y Cao,L Li,Z Feng,et al.Comparative genetic analysis of the novel coronavirus(2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations[J].Cell Discov,2020,6:11.
[16] PIL A,YLH B,PYC C,et al.Are children less susceptible to COVID-19?[J].J Microbiol Immunol Infect,2020,53(3):371-372.
[17] PHQ A,JW A,HB Liang,et al.Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang,China:an observational cohort study[J].The Lancet Infectious Diseases,2020,20(6):689-696.
[18] 应艳琴,温宇,赵瑾珠等.2019新型冠状病毒病流行期间儿童分级防控建议[J].中国儿童保健杂志,28(3):237-241.
[19] 吴倩,魏丽丽,陈蕾等.新型冠状病毒感染疫情的儿童社区防控[J].全科护理,2020,18(6):713-715.
基金
安徽省科技厅、安徽省卫健委应急科研攻关项目“新冠肺炎流行病学及临床特征研究”,项目编号:202004a07020002;“新型冠状病毒分子变异与进化研究”,项目编号:202004a07020004。