我国治疗前HIV耐药毒株流行进展

陈宏利, 李丹, 冯毅, 阮玉华

安徽预防医学杂志 ›› 2024, Vol. 30 ›› Issue (1) : 34-38.

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安徽预防医学杂志 ›› 2024, Vol. 30 ›› Issue (1) : 34-38. DOI: 10.19837/j.cnki.ahyf.2024.01.008
艾滋病防治专栏

我国治疗前HIV耐药毒株流行进展

  • 陈宏利, 李丹, 冯毅, 阮玉华
作者信息 +

Progress in the prevalence of pretreatment HIV resistant strains in China

  • CHEN Hongli, LI Dan, FENG Yi, RUAN Yuhua
Author information +
文章历史 +

摘要

HIV耐药毒株的流行影响了抗逆转录病毒治疗(ART)效果,降低了HIV感染者体内病毒抑制率并导致HIV的二代传播。HIV感染者尚不能治愈,需要终身服药。一旦由于某种原因导致治疗失败,可能会出现HIV耐药毒株,导致HIV耐药在我国未治疗人群中产生并传播。本文就我国治疗前HIV耐药毒株流行的研究进展进行了文献综述。

Abstract

The prevalence of HIV resistant strains has affected the effectiveness of antiretroviral therapy,reducing the viral inhibition rate in HIV-infected individuals and leading to second-generation transmission of HIV.HIV infected individuals cannot be cured yet and require lifelong medication.Once treatment fails due to various reasons,drug-resistant strains of HIV may emerge,which may lead to the emergence and spread of HIV resistance among the untreated population in China.This article provides a literature review on research progress of pretreatment HIV resistant strains in China.

关键词

治疗前 / 艾滋病病毒 / 耐药毒株。

Key words

Pretreatment / HIV / Drug-resistant strains

引用本文

导出引用
陈宏利, 李丹, 冯毅, 阮玉华. 我国治疗前HIV耐药毒株流行进展[J]. 安徽预防医学杂志. 2024, 30(1): 34-38 https://doi.org/10.19837/j.cnki.ahyf.2024.01.008
CHEN Hongli, LI Dan, FENG Yi, RUAN Yuhua. Progress in the prevalence of pretreatment HIV resistant strains in China[J]. Anhui Journal of Preventive Medicine. 2024, 30(1): 34-38 https://doi.org/10.19837/j.cnki.ahyf.2024.01.008
中图分类号: R512.91   

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基金

国家科技部十四五重大专项(2022YFC2305205);国家自然科学基金(82260670);广西艾滋病防控与成果转化研究重点实验室(ZZH2020010);广西八桂学者艾滋病防控关键技术岗位专项;广西医疗卫生重点学科建设项目

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