目的 了解新型冠状病毒感染(COVID-19)病例感染毒株类型、临床分型、重症率及住院费用等情况,为该病的防治提供参考依据。方法 收集2022年11月至2023年1月中国科学技术大学附属第一医院感染病院区(合肥市传染病院)收治的COVID-19病例相关信息,计算感染毒株构成比、临床分型构成比、重症率和治疗费用等相关指标,采用SPSS 26.0进行统计学分析。结果 共调查90例COVID-19病例,其中男性63例,女性27例,年龄为27～96岁;临床分型为轻型32例(占35.56%),普通型47例(占52.22%),重型11例(占12.22%);感染毒株分布为BA.5.2.48感染者57例(占63.33%),BF.7.14感染者25例(占27.78%),其他亚型感染者8例(占8.89%);伴基础疾病病例50例(占55.56%),无基础疾病病例40例(占44.44%)。重症病例住院费用高于普通型病例和轻型病例(H = 32.658,P＜0.001),伴基础疾病病例住院费用高于无基础病病例(Z =5.903,P＜0.001)。伴基础疾病者重症率(20.00%)高于无基础疾病者(2.50%)(PFisher=0.019)。结论 COVID-19病例以普通型和轻型为主,感染毒株以BA.5.2.48和BF.7.14为主,重症病例和伴基础疾病病例的治疗费用较高。
Abstract
Objective To understand the strains type,clinical typing,severity rate and hospitalization costs of COVID-19 cases,and provide reference basis for the prevention and treatment. Methods Relevant information to COVID-19 cases admitted to the First Affiliated Hospital of the University of Science and Technology of China,Infectious Disease Hospital Area (Hefei Infectious Disease Hospital) from November 2022 to January 2023 was collected,the proportion of strains,clinical subtypes,severity rate,treatment costs,and other related indicators were calculated.Perform statistical analysis using SPSS 26.0. Results A total of 90 COVID-19 cases were investigated,including 63 males and 27 females,aged from 27 to 96 years old.32 cases were mild from clinical classification (35.56%),47 cases were common (52.22%),and 11 cases were severe (12.22%).The distribution of strains were as follows: 57 cases (63.33%) were infected with BA.5.2.48,25 cases (27.78%) were infected with BF.7.14,and 8 cases (8.89%) were infected with other subtypes.There were 50 cases (55.56%) with underlying diseases and 40 cases (44.44%) without underlying diseases.The hospitalization cost of severe cases was higher than that of ordinary cases and mild cases (H=32.658,P<0.001),and the hospitalization cost of cases with underlying diseases was higher than those without underlying diseases (Z =5.903,P＜0.001).The severity rate of patients with underlying diseases (20.00%) was higher than that of those without underlying diseases (2.50%) (PFisher=0.019). Conclusion COVID-19 cases are mainly common and mild,with the main strains of BA.5.2.48 and BF.7.14.The treatment costs for severe cases and cases with underlying diseases are relatively high.
关键词
新型冠状病毒感染 /
新型冠状病毒 /
临床特征 /
住院
Key words
COVID-19 /
SARS-CoV-2 /
Clinical features /
Hospitalization expenses
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基金
中国公共卫生联盟基金项目(GWLM202112);合肥市第七周期重点学科建设项目资助(Z033-1)
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