目的 分析福建省永安市恶性肿瘤发病和死亡情况与变化趋势,为恶性肿瘤的防控工作提供依据。方法 收集2014—2020年永安市肿瘤登记处恶性肿瘤发病和死亡资料,计算恶性肿瘤发病率、标化发病率、死亡率、标化死亡率、年度变化百分比(APC)、平均年度变化百分比(AAPC),进行时间趋势分析。结果 2014—2020年永安市恶性肿瘤年均报告发病率和死亡率为293.76/10万和167.74/10万,标化发病率和标化死亡率为233.79/10万和128.57/10万。永安市全人群恶性肿瘤发病率(APC=5.69%,t=5.854,P=0.002)和标化发病率(APC=4.47%,t=5.713,P=0.002)呈上升趋势,死亡率(APC=0.64%,t=0.428,P=0.687)和标化死亡率(APC=-1.71%,t=-1.230,P=0.273)随时间变化趋势差异无统计学意义。永安市恶性肿瘤发病居前5位病种依次为肺癌(占18.92%)、结直肠癌(占14.06%)、胃癌(占9.37%)、肝癌(占8.73%)、乳腺癌(占7.39%),死亡居前5病种依次为肺癌(占24.64%)、肝癌(占13.32%)、胃癌(占12.42%)、结直肠癌(占12.22%)、食管癌(占5.70%);恶性肿瘤发病率和死亡率在30岁及以上人群随着年龄增长而上升。结论 永安市恶性肿瘤发病率呈上升趋势,应对常见癌种和不同人群实施针对恶性肿瘤的综合防控措施。

Objective To analyze the cancer incidence,mortality and trends in Yong'an of Fujian Province from 2014 to 2020,and to provide the scientific basis for cancer prevention and control. Methods From 2014 to 2020,the incidence and death data of malignant tumors in Yong'an Cancer Registry were selected to calculate the incidence rate,standardized incidence rate,mortality,standardized mortality,annual percentage change (APC),average annual percentage change (AAPC) of malignant tumors.The time trend analysis was conducted. Results From 2014 to 2020,the average annual incidence rate and mortality rate of malignant tumors were 293.76/100 000 and 167.74/100 000,the standardized incidence rate and standardized mortality rate were 233.79/100 000 and 128.75/100 000.The incidence rate of malignant tumors (APC=5.69%,t=5.854,P=0.002) and the standardized incidence rate (APC=4.47%,t=5.713,P=0.002) of the whole populations in Yong'an showed an upward trend.The mortality rate (APC=0.64%,t=0.428,P=0.687) and the standardized mortality rate (APC=-1.71%,t=-1.230,P=0.273) had no statistically significant differences over time.The top five malignant tumors in Yong'an were lung cancer (18.92%),colorectal cancer (14.06%),stomach cancer (9.37%),liver cancer (8.73%),breast cancer (7.39%).The top five tumors of death were lung cancer (24.64%),liver cancer (13.32%),stomach cancer (12.42%),colorectal cancer (12.22%),and esophageal cancer (5.70%).The incidence rate and mortality rate of malignant tumors increased with age at 30 years old and above. Conclusion The incidence rate of malignant tumors in Yong'an is on the rise,and comprehensive prevention and control measures for malignant tumors should be implemented for common cancers and different populations.