目的 分析2013—2024年江苏省徐州市生殖道沙眼衣原体感染的流行特征与空间分布，为制定精准防控策略提供依据。方法 利用中国疾病预防控制信息系统，收集2013—2024年徐州市生殖道沙眼衣原体感染病例数据，采用描述性流行病学方法分析其三间分布，运用Joinpoint回归模型分析发病率变化趋势，并利用GeoDa 1.20.0软件进行空间自相关分析。结果 2013—2024年徐州市累计报告生殖道沙眼衣原体感染病例1970例，年均报告发病率为1.84/10万，总体呈上升趋势（AAPC=15.91%，P=0.003，95%CI：6.00~31.96）。病例以女性（65.23%）为主，年龄集中分布于20~29岁（41.02%），职业以家务及待业（45.18%）和农民（34.21%）为主。地区分布中，云龙区年均发病率最高（3.40/10万），丰县最低（0.77/10万）。空间分析显示，2016年及2021—2024年报告发病率存在空间正相关性（Moran’s I >0, P值均<0.05），存在空间聚集效应。结论 2013—2024年徐州市生殖道沙眼衣原体感染报告发病率呈上升趋势，并呈现空间聚集特征。

Objective To analyze the epidemiological characteristics and spatial distribution of genital Chlamydia trachomatis infection in Xuzhou of Jiangsu Province from 2013 to 2024, and to provide evidence for formulating precise prevention and control strategies. Methods The data of cases with genital Chlamydia trachomatis infection in Xuzhou from 2013 to 2024 were collected from the China Disease Prevention and Control Information System. Descriptive epidemiological methods were employed to analyze the temporal, population, and geographical distribution. The Joinpoint regression model was used to analyze the trend of incidence rate, and spatial autocorrelation analysis was performed by using GeoDa 1. 20. 0 software. Results From 2013 to 2024, a total of 1 970 cases of genital Chlamydia trachomatis infection were reported in Xuzhou, with an average annual reported incidence rate of 1.84/100 000. The overall reported incidence showed a significant increasing trend (AAPC=15.91%, 95%CI：6.00-31.96, P=0.003). Most cases were female (65.23%), aged 20-29 years (41.02%), and whose occupations were predominantly homemakers/unemployed individuals (45.18%) and farmers (34.21%). The highest and lowest average annual incidence rates were observed in Yunlong District (3.40/100 000) and Feng County (0.77/100 000), respectively. Spatial autocorrelation analysis indicated a positive spatial correlation of reported incidence rates in the years 2016 and 2021-2024 (Global Moran’s I >0, all P<0.05), suggested spatial clustering effects. Conclusion The reported incidence rate of genital Chlamydia trachomatis infection in Xuzhou increased from 2013 to 2024, with evident spatial clustering characteristics.