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2017—2022年赣州市甲状腺癌流行特征及趋势分析
严月康, 王小毛, 谭颖, 蔡永, 袁雪茜, 朱瑶琴
安徽预防医学杂志 ›› 2026, Vol. 32 ›› Issue (3) : 234-239.
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2017—2022年赣州市甲状腺癌流行特征及趋势分析
Epidemiological characteristics and trends of thyroid cancer in Ganzhou City from 2017 to 2022
目的 分析2017—2022年江西省赣州市肿瘤登记地区甲状腺癌发病与死亡情况及其变化趋势。方法 收集赣州市肿瘤登记处上报、经质控合格的ICD-10编码为C73的甲状腺癌病例数据，按性别、年龄组和城乡分别计算发病（死亡）率、中国人口年龄标准化发病率（简称中标率）、累积率（0~74岁）、截缩率（35~64岁）等指标，采用Joinpoint软件计算平均年度变化百分比（average annual percentage change, AAPC），分析2017—2022年变化趋势。结果 2017—2022年，赣州市肿瘤登记地区甲状腺癌粗发病率为9.84/10万（中标率为10.42/10万）；0~74岁累积发病率为0.74%，35~64岁截缩发病率为16.39/10万；女性发病率显著高于男性（χ2=749.061，P<0.001）；城市发病率高于农村（χ2=424.870，P<0.001）。甲状腺癌粗死亡率为0.55/10万（中标率为0.50/10万），0~74岁累积死亡率为0.04%，35~64岁截缩死亡率为0.63/10万。发病率和死亡率分别自25~29岁和55~59岁年龄组起大幅上升，高峰分别集中在50~54岁年龄组（18.86/10万）和≥85岁年龄组（5.06/10万）。甲状腺癌发病率呈上升趋势（AAPC=41.41%，95%CI：25.53%~70.01%，t=3.649，P<0.001），其中男性、女性、城市和农村发病率和中标发病率均呈上升趋势（P均<0.05）；甲状腺癌死亡率呈上升趋势（AAPC=27.05%，95%CI：4.94%~66.13%，t=1.733，P=0.010），其中男性和农村的粗死亡率、中标死亡率均呈上升趋势（P均<0.05）。结论 赣州市甲状腺癌发病率和死亡率均呈快速上升趋势，发病率呈现女性高于男性、城市高于农村的特点，需因地制宜制定防控措施，以降低甲状腺癌的疾病负担。
Objective To analyze the incidence and mortality of thyroid cancer and their temporal trends in the cancer registry areas of Ganzhou City, Jiangxi Province from 2017 to 2022. Methods Data on thyroid cancer cases with ICD-10 code C73, reported by cancer registries in Ganzhou City and approved through quality control, were collected. Incidence (mortality) rates, age-standardized rates (standardized to the Chinese standard population), cumulative rates (0-74 years), and truncated rates (35-64 years) were calculated by sex, age group, and area (urban/rural areas). Joinpoint software was used to calculate the average annual percentage change (AAPC) and analyze the trends from 2017 to 2022. Results From 2017 to 2022, the crude incidence rate of thyroid cancer in the Ganzhou City cancer registry areas was 9.84/100 000 [age-standardized incidence rate by Chinese standard population (ASIRC)=10.42/100 000]. The cumulative incidence rate of 0-74 years old was 0.74%, and the truncated incidence rate of 35-64 years old was 16.39/100 000. The incidence rate among women was significantly higher than that among men (χ2=749.061, P<0.001), and the incidence rate in urban areas was higher than that in rural areas (χ2=424.870, P<0.001). The crude mortality rate of thyroid cancer was 0.55/100 000 [age-standardized mortality rate by Chinese standard population (ASMRC)= 0.50/100 000]. The cumulative mortality rate of 0-74 years old was 0.04%, and the truncated mortality rate of 35-64 years old was 0.63/100 000. The incidence and mortality rates increased substantially starting at the 25-29 and 55-59 age groups, respectively, with peaks concentrated in the 50-54 age group (18.86/100 000) and the ≥85 age group (5.06/100 000). Thyroid cancer incidence showed an upward trend (AAPC=41.41%, 95%CI: 25.53%-70.01%, t=3.649, P<0.001), with both crude and age-standardized incidence rates increasing among males, females, urban and rural populations (all P<0.05). Thyroid cancer mortality showed an upward trend (AAPC=27.05%, 95%CI: 4.94%-66.13%, t=1.733, P=0.010), with both the crude mortality rate and the ASMRC rising among males and in rural areas (all P<0.05). Conclusion The incidence and mortality of thyroid cancer in Ganzhou City increased rapidly. The incidence was higher in women than in men, and higher in urban areas than in rural areas. Tailored prevention and control measures should be developed according to local conditions to reduce the burden of thyroid cancer.
甲状腺癌 / 发病率 / 死亡率 / 流行病学特征 / 趋势分析
Thyroid cancer / Incidence rate / Mortality rate / Epidemiological characteristics / Trend analysis
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