目的 通过对江西省首例人感染H5N6禽流感病例的调查分析,探讨人感染H5N6禽流感感染因素。方法 调查病例的发病就诊经过、可能的暴露来源,医学观察密切接触者,采集病例鼻咽拭子标本、暴露环境标本进行实验室检测,运用描述流行病学方法进行分析。结果 江西省首例人感染H5N6禽流感患者,咽拭子标本检测为H5N6禽流感病毒核酸阳性,为外地感染,有活禽暴露史,医学观察密切接触者25人未发现异常;病例明确诊断较晚,有基础性疾病史,早期缺乏针对性治疗,导致病情加重,最后因呼吸衰竭死亡。结论 江西省人感染H5N6禽流感病例可能与活禽暴露有关。
Abstract
Objective To analyze the first case infected with avian influenza A (H5N6) virus in Jiangxi province, and provide scientific basis for prevention and control strategies. Methods Research was carried out by investigating medical process and possibly exposure source of the case, together with taking a medical observation of close contacts of the patient, and collecting samples of pharyngeal swab and environmental exposure for laboratory testing in addition, thereby analyzed by description epidemiology. Results Pharyngeal swab specimen of the case was tested positive for H5N6 avian flu virus nucleic acid, with the infection from other regions and once exposed to live poultry, no abnormal was found from medical observation of 25 close contacts. Case was confirmed with H5N6 virus infection late and had a history of basic diseases, however, was not on targeted therapies at early time, resulting in worse illness, and died of respiratory failure finally. Conclusion The case infected by Human avian influenza A (H5N6)virus in Jiangxi province is related to live poultry exposure.
关键词
人感染H5N6禽流感 /
新发传染病 /
流行病学 /
暴露因素
Key words
Human infection with avian influenza A (H5N6) virus /
Emerging infectious disease /
Epidemiology /
Exposure factor
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