目的 估算安徽省2015年先天梅毒发病率。方法 收集传染病报告信息管理系统和母婴阻断直报系统中安徽省2015年报告的先天梅毒人数,根据安徽省助产机构年报表获取2015年新生儿活产数,对全省15家医疗保健机构开展先天梅毒报告病例核实调查。据此进行先天梅毒发病水平的估算。结果 2015年传染病直报系统共报告先天梅毒323例,母婴阻断直报系统报告5例先天梅毒,助产机构共报告活产数751 132人。以传染病直报系统数据为基础,测算出2015年全省先天梅毒人数约为128~200例,为实际上报病例数(323例)的39.3%~61.9%,先天梅毒发病率约为17.0/10万~26.6/10万;根据母婴阻断直报系统数据,测算出2015年全省先天梅毒人数为99~158例,为实际上报病例数的19.8~31.6倍,先天梅毒发病率约为13.2/10万~21.0/10万。结论 采用两种估算方法测算安徽省2015年先天梅毒发病率在13/10万~26/10万之间。

Objective To estimate the incidence of congenital syphilis in 2015 in Anhui province. Methods Reported numbers of congenital syphilis in 2015 in Anhui province were collected from the Information System of the National Disease Prevention and Control (DC information system) and the Information System of the Prevention of Maternal to Child Transmission of HIV, Syphilis and Hepatitis B (PMTCT information system).The number of newborns in 2015 was collected from the hospital report.Relevant indicators were collected from the. Results the evaluation of reported congenital syphilis cases in 2015 in Anhui. Results In 2015, the DC information system reported 323 congenital syphilis cases, the PMTCT information system reported 5 cases, and there were 751132 newborns reported by hospitals in Anhui province.Based on the DC information system, the estimated congenital syphilis cases were 128-200, which were 39.3-61.9% of the reported number.The estimated incidence was 17.0/10⁵-26.6/10⁵.Based on the PMTCT information system, the estimated congenital syphilis cases were 99-158,which were 19.8-31.6 of the reported number.The estimated incidence was 13.2/10⁵-21.0/10⁵. Conclusion In 2015 in Anhui province, the estimated incidence rate of congenital syphilis was 13-26/10⁵, using 2 estimation methods.