目的 通过对疫情调查处置,分析疫情发生原因。方法 对疫情发生的学校,开展现场流行病学调查,并采集部分患者肛拭子标本进行诺如病毒核酸检测。结果 共14名学生发病,6例肛拭子标本诺如病毒GⅡ型核酸阳性,病例对照分析显示,学生周边1 m内是否有呕吐物的罹患水平(χ2=11.67,P<0.05)、身边是否有患病学生的罹患水平(χ2=7.47,P<0.05),差异均有统计学意义。结论 该起聚集性疫情是由诺如病毒感染引起,近距离飞沫传播和吸入含有呕吐物的气溶胶可能是导致疫情播散的主要因素。
Abstract
Objective Through the investigation and disposal of the epidemic,the causes of the outbreak were analyzed. Methods In the school where the epidemic occurred,field epidemiological investigation was carried out,and the anal swabs of some patients were collected for norovirus nucleic acid detection. Results A total of 14 students suffered from the disease,and 6 anal swab samples were positive for norovirus GⅡnucleic acid.Case comparison analysis showed that there were statistically significant differences in the norovirus infection rates of whether vomit were within 1 m around the students (χ2=11.67,P<0.05),and in the norovirus infection rate of whether there were norovirus patients around the students (χ2=7.47,P<0.05). Conclusion This aggregative epidemic was caused by norovirus infection,and the spread of the epidemic may be mainly caused by close-up droplets and inhalation of aerosols containing vomitus.
关键词
诺如病毒 /
聚集性疫情 /
学校 /
胃肠炎 /
飞沫传播 /
气溶胶
Key words
Norovirus /
Aggregative epidemic /
School /
Gastroenteritis /
Droplet transmission /
Aerosol
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 廖巧红,冉陆,靳淼,等.诺如病毒感染暴发调查和预防控制技术指南 (2015版)[J].中国病毒病杂志,2015,5(6):448-458.
[2] 李红梅.诺如病毒研究进展[J].华夏医学,2013,26(4):856-859.
[3] 吴振宇,张德勇,雷永良.一起经气溶胶传播的学校诺如病毒暴发调查[J].中国学校卫生,2012,33(2):244-245.
[4] 姜璎慈,马飞飞,李琮,等.江苏省苏州市某学校诺如病毒引起的腹泻暴发现场流行病学调查[J].疾病监测,2015,30(12):1070-1071.
[5] 陈兴付,魏征,冯花平,等.一起小学诺如病毒感染性腹泻暴发疫情的调查报告[J]安徽预防医学杂志,2018,24(1):51-51,66.
[6] 罗乐,王曼,朱亚阳,等.中山市1起诺如病毒感染暴发调查[J].热带医学杂志,2017,17(4):540-542.
[7] 吴文倩.南京市一起学校诺如病毒暴发疫情调查[J].现代医学,2018,46(12):1360-1363.
[8] 张爱华,郭海燕.1起诺如病毒感染性腹泻聚集性疫情调查[J].预防医学论坛,2018,24(11):855-856,863.
[9] 莫瑜洁,王晓龙,闫润泽.上海嘉定区一起学校诺如病毒GⅡ型感染性腹泻聚集性疫情流行特征分析[J].上海医药,2018,39(18):49-51.
[10] 周印,袁兆虎,张万军,等.1起疑似气溶胶传播的诺如病毒暴发疫情调查[J].江苏预防医学,2016,27(6):722,750.