目的 分析芦溪县手足口病近10年来发病趋势,了解流行特点。方法 根据传染病报告信息管理系统监测数据,采用描述性流行病学方法,对芦溪县2009~2018年手足口病病例信息及病原学监测数据进行分析。结果 芦溪县2009~2018年手足口病年均报告发病率383.97/10万,发病水平总体呈上升趋势(χ²_趋势=3 675.626,P＜0.001)。5岁以下儿童的病例占90.11%,其中以1岁年龄组的婴幼儿发病数最多,占40.14%。手足口病呈隔年出现持续1~2年高发的周期性流行及3~7月、9~11月“双峰”季节性流行特征。手足口病病原学总阳性率为54.08%,其中重症患者病原阳性率100.00%、以EV71型病毒阳性为主;聚集性、普通病例阳性率分别75.00%、49.71%,以其他肠道病毒、CoxA16病毒阳性为主。结论 芦溪县手足口病发病呈上升趋势,应进一步采取综合防控措施,控制手足口病发病水平。

Objective To analyze the trend of hand,foot and mouth disease (HFMD) in Luxi County in the past 10 years and understand the epidemic characteristics. Methods According to the surveillance data of Infectious Disease Report Information Management System,descriptive epidemiological method was used to analyze the case information and pathogenic surveillance data of HFMD in Luxi County from 2009 to 2018. Results From 2009 to 2018,the annual reported incidence of HFMD in Luxi County was 383.97/100000,and the incidence level showed an upward trend (χ²_trend=3 675.626,P<0.001). Children under 5 years old accounted for 90.11% of the cases,of which the incidence of infants in the 1-year-old group was the most,accounting for 40.14%. HFMD was a periodic epidemic with a high incidence of 1-2 years every other year,and had the seasonal epidemic characteristic of "double peak" in March to July and September to November. The total positive rate of HFMD was 54.08%,in which the positive rate of severe cases was 100%,mainly EV71. The positive rate of aggregative cases and common cases were 75.00% and 49.71% respectively,mainly other enteroviruses and CoxA16. Conclusion The incidence of HFMD in Luxi County was on the rise,and comprehensive prevention and control measures should be taken to control the incidence of HFMD.