目的 通过调查处置成都市新都区某农家乐发生的疑似食源性疾病聚集性疫情,分析疫情发生的原因和暴露危险因素。方法 根据疫情发生情况,采取现场流行病学调查,描述疫情三间分布,分析疫情发生的可疑因素,开展病例对照研究验证引起疫情的可能原因。采集病例及农家乐员工生物样本、留样菜品、饮水、餐具和环境涂抹样共计54份,进行细菌学检测和诺如病毒核酸检测。结果 本次疫情共计病例16例,罹患率为7.8%;隐性感染者2例。发病的客人16例,均在某农家乐共同食宿。病例对照研究发现,蒸酥肉是发病风险最高的可疑食物(OR=5.13,95%CI:1.23~21.36),近距离接触病例造成疾病传播的危险因素(OR=6.50,95%CI:1.39~30.37)。在10份生物样本和1份环境样本中检出诺如病毒核酸阳性。结论 本次感染性腹泻聚集性疫情由诺如病毒引起,可能是食源性传播和人与人接触传播共同作用的结果。
Abstract
Objective To investigate and deal with a suspected food borne disease clustering epidemic in an agritainment resort,Xindu District,Chengdu City,and analyze the causes of the epidemic and the risk factors of exposure. Methods According to the occurrence of the epidemic,field epidemiological investigation was carried out to describe the spatial,temporal and population distribution of the epidemic,analyze the suspicious factors of the epidemic,and carry out case-control study to verify the possible causes of the epidemic.A total of 54 samples from patients and agritainment resort employees of biological samples,preserved dishes,drinking water,tableware and environmental smears were collected for bacteriological and norovirus nucleic acid detection. Results There were 16 cases in this epidemic,the incidence rate was 7.8%,and 2 cases of recessive infection.16 patients were affected,all of whom shared room and board.In the case-control study,steamed crisp meat was the most dangerous food (OR=5.13,95% CI:1.23-21.36),and the risk factors of disease transmission caused by close contact with the case (OR=6.50,95% CI:1.39-30.37).Norovirus DNA was detected in 10 biological samples and 1 environmental sample. Conclusion The clustering epidemic of infectious diarrhea was caused by norovirus,which may be the result of the joint action of food borne transmission and human to human contact transmission.
关键词
诺如病毒 /
感染性腹泻 /
聚集性
Key words
Norovirus /
Infectious diarrhea /
Clustered
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 李世娥,周浩,刘金茹,等.一起高校诺如病毒感染性腹泻暴发疫情的调查[J].黑龙江医学,2018,42(6):596-598.
[2] 中国疾病预防控制中心.诺如病毒感染暴发调查和预防控制技术指南(2015版)[M].传染病专报,2015,3(37).
[3] 陈阿群,高淑萍,孙立梅,等.2014年广州某大学一起诺如病毒感染性腹泻暴发疫情的调查分析[J].应用预防医学,2016,22(1):15-18.
[4] 刘红联,汤泓,夏仪,等.一起学校诺如病毒聚集性疫情的病例对照调查[J].上海预防医学,2018,30(4):304-306.
[5] 宗俊,陶瑞华,潘欢弘.2015年江西省某砖瓦厂诺如病毒性胃肠炎暴发调查[J].江西医药,2017,52(9):931-933.
[6] 温雅,文艳群,唐旭,等.某酒楼一起诺如病毒胃肠炎聚集性疫情流行病学调查[J].中国初级卫生保健,2018,32(8):38-40.
[7] 陈建梅,董建元,张思华,等.一起诺如病毒引起的感染性腹泻暴发疫情调查分析[J].安徽预防医学杂志,2017,23(5):335-338.
[8] 吴杨,刘凯,李世聪,等.一起诺如病毒急性胃肠炎暴发疫情调查分析[J].应用预防医学,2018,24(1):72-73.
[9] 高慧娟,何凡,郭敏建,等.一起诺如病毒引起的急性胃肠炎暴发调查[J].浙江预防医学,2015,27(7):721-723.
[10] 陈秀兰,薛士银,刘从高.一起诺如病毒引起的感染性腹泻暴发调查[J].江苏预防医学,2015,26(6):89-90.