目的 通过调查三水区一起小学流行性腮腺炎暴发疫情,分析疫情发生原因,探讨含腮腺炎成分疫苗接种对疫情控制的影响。方法 根据传染病报告信息管理系统流行性腮腺炎监测数据及现场流行病学调查资料,分析三水区某小学流行性腮腺炎暴发疫情特点,疫情发生原因及含腮腺炎成分疫苗接种水平对腮腺炎发病的影响。结果 三水区某小学发生流行性腮腺炎暴发疫情,疫情持续64d,累计42名学生发病,罹患率1.38%,六年级学生罹患率高于其他年级学生罹患率(χ2=124.54,P<0.05),六年级学生既往接种1剂次含腮腺炎成分疫苗保护率为46.67%,疫情暴发期间,六年级学生应急接种率为29.59%,应急接种疫苗保护率为100%,调查发现共有6例流腮病例学校未及时隔离是暴发疫情发生的主要影响因素。结论 首发病例没有及时隔离,疫情期间学校组织班级交叉考试,可能是该起暴发疫情发生的主要原因,六年级学生既往接种1剂次含腮腺炎成分疫苗保护效果不理想、应急接种率低、是该起疫情持续蔓延的重要因素。
Abstract
Objective To investigate an outbreak of mumps in primary schools in Sanshui District, analyze the causes of the outbreak, and explore the effect of mumps component vaccination on epidemic control. Methods According to the monitoring data of mumps in the information management system of infectious diseases report, and the data of field epidemiological investigation, this paper analyzed the characteristics of the outbreak of mumps in a primary school in Sanshui District, the causes of the outbreak and the influence of the level of mumps component vaccination on the incidence of mumps. Results There was an outbreak of mumps in a primary school in Sanshui District, which lasted for 64 days.The incidence of mumps in 42 students was 1.38%.The incidence of mumps in Grade 6 was higher than that in other grades (χ2= 124.54,P<0.05),the protection rate of one dose of mumps containing vaccine for Grade 6 students was 46.67%, the emergency vaccination rate of grade 6 students was 29.59%, and the emergency vaccination protection rate was 100%.It was found that 6 mumps cases were not isolated in school in time. Conclusion Failure to isolate the first case in time and the school’s cross-examination of classes during the epidemic may be the main reason for the outbreak.The previous vaccination of grade 6 students with mumps containing component vaccine was not ideal, and the low emergency vaccination rate may be important factors in the continuous spread of the epidemic.
关键词
流行性腮腺炎 /
暴发疫情 /
应急接种 /
传染病 /
突发公共卫生事件
Key words
Mumps /
Outbreak /
Investigation and analysis /
Emergency vaccination /
Infectious diseases /
Public health emergencies
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 李兰娟,任红.传染病学[M].北京:人民卫生出版社,2014:73.
[2] 广东省疾病预防控制中心.广东省风疹、流行性腮腺炎、水痘暴发疫情调查处理技术指引(试行)[EB/OL].[2012-5-21].https://max.book118.com/html/2015/0426/15761942.shtm.
[3] 蔡文锋,阮峰,张冬生,等.一起流行性腮腺炎暴发疫情的现场流行病学调查[J].华南预防医学,2013,39(5):46-48.
[4] 徐娟,栾琳,张钧,等.苏州市某中学一起流行性腮腺炎疫情调查和应急接种效果评价[J].公共卫生与预防医学,2019,30(6):90-101.
[5] 郭强,云忠平.一起学校流行性腮腺炎爆发疫情的调查报告[J].疾病监测与控制杂志,2016,6(10):490-492.
[6] 张辉,刘继锋,龚建仁.西安市一起学校流行性腮腺炎暴发疫情调查[J].现代预防医学杂志,2016,43(8):1495-1498.
[7] 随海田,马小军,黄丽红,等.福建省莆田市涵江区2015年一起小学流行性腮腺炎暴发的调查[J].中国疫苗和免疫,2016,22(5):525-529.
[8] 王青海,张璐,卢渝军,等.2016 年北京市西城区第二剂麻腮风疫苗复种效果监测分析[J].中华微生物学和免疫学杂志,2017,37(7): 557-559.
[9] 秦伟,刘艳,张丽杰,等.安徽省六安市学校流行性腮腺炎暴发现场含腮腺炎成分疫苗保护效果评估[J].疾病监测,2018,33(8): 659-663.
[10] 曹雪梅.一起学校流行性腮腺炎暴发疫情的调查分析[J].中国卫生标准管理,2015,16(6):1-2.
[11] 王延庆,王延田.育龄妇女接种麻疹疫苗对婴儿麻疹发病影响的研究[J].中国预防医学杂志,2016,17(9):693-697.
[12] 苏磊静,包红红,冯辉煌.北海市流行性腮腺炎发病的相关影响因素分析[J].职业与健康,2016,32(20):2867-2869,2872.
[13] 黄晓玉,黄肇林,罗盛.应急接种控制流行性腮腺炎疫情的效果[J].预防医学情报杂志,2016,30(4):285-287.
[14] 朱琦,张恒,韩轲,等.广州市一起幼儿园流行性腮腺炎暴发疫情调查[J].现代预防医学,2013,34(2):199-201.