目的 分析镜湖区居民恶性肿瘤死亡特征及变化趋势,为科学制定肿瘤防治政策提供依据。方法 通过中国疾病预防控制信息系统收集2014—2020年镜湖区居民恶性肿瘤资料,计算死亡率、标化死亡率、年龄别死亡率、死因顺位、死亡趋势、年度变化百分比(APC),分析恶性肿瘤死亡趋势。结果 2014—2018 年芜湖市镜湖区居民肿瘤死亡率上升(APC=4.68%,P=0.173) ,2018—2020年下降(APC=-6.24%,P=0.451),但差异无统计学意义。2014—2018年男性恶性肿瘤死亡率上升(APC＝3.85%,P=0.019),2018—2020年下降(APC＝7.57%,P=0.040),两个时段变化均有统计学意义;2014—2020年女性恶性肿瘤死亡率呈上升趋势,但差异无统计学意义(t=1.310,P=0.250)。2014—2020年恶性肿瘤死因顺位前5位是肺癌、胃癌、结肠直肠肛门癌、肝癌、食道癌,除肺癌死亡率呈下降趋势,其余4种恶性肿瘤死亡率均呈上升趋势。结论 肺癌、肝癌、胃癌、食管癌、结直肠癌及乳腺癌是威胁镜湖区居民健康状况的重要疾病,应加强重点恶性肿瘤的防治工作。
Abstract
Objective To analyze the characteristics and trend of malignant tumor mortality in Jinghu District,and to provide scientific basis for cancer prevention and control policy. Methods The data of malignant tumor in Jinghu District from 2014 to 2020 were collected through the Chinese Disease Control and prevention information system,mortality rate,standardized mortality rate,age-specific mortality rate,cause of death order,mortality trend,annual percentage change (APC) were calculated and analyzed. Results The trend of tumor mortality in men and women increased from 2014 to 2018(APC=4.68%,P= 0.173) and decreased from 2018 to 2020(APC=-6.24%,P= 0.451) ,but the difference was not statistically significant.Mortality from malignancy in men increased from 2014 to 2018 (APC=3.85%,P= 0.019) ,and decreased from 2018 to 2020 (APC=-7.57%,P= 0.040) ,with statistically significant changes over both time periods.The mortality rate of malignant tumors in females showed an upward trend from 2014 to 2020,but the difference was not statistically significant (P=0.250).From 2014 to 2020,lung cancer,stomach cancer,colorectal cancer,liver cancer and esophageal cancer were the top five causes of death,except for the lung cancer mortality,the other four kinds of mortality showed an upward trend. Conclusion Lung cancer,liver cancer,stomach cancer,esophageal cancer,colorectal cancer and breast cancer are important diseases threatening the health of residents in Jinghu District.The prevention and treatment of key malignant tumors should be strengthened.
关键词
恶性肿瘤 /
死亡率 /
死因顺位 /
Joinpoint分析 /
年度变化百分比(APC)
Key words
Malignant tumor /
Mortality /
Rank of death causes /
Joinpoint regression /
Annual percentage change (APC)
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 刘宗超,李哲轩,张阳,等.2020全球癌症统计报告解读[J].肿瘤综合治疗电子杂志,2021,7(2) :1-14.
[2] 陈竺.全国第三次死因回顾抽样调查报告[M].北京:中国协和医科大学出版社,2008.
[3] WHO.Global Health Estimates 2020:Deaths by Cause,Age,Sex,by Country and by Region,2000-2019[Z/OL].(2021-02-20)[2022-07-28].https://www.who.int/data/gho/data/themes/mortality-andglobal-health-estimates/ghe-leading-causes-of-death.
[4] 王临虹.慢性非传染性疾病预防与控制[M].北京:人民卫生出版社,2018.
[5] 郑莹,吴春晓,张敏璐.乳腺癌在中国的流行状况和疾病特征[J].中国癌症杂志,2013,23(8):561-569.
[6] 黄育北,佟仲生,陈可欣,等.《中国女性乳腺癌筛查指南》解读(精简版)[J].中国肿瘤临床,2019(9):432-440.
[7] Kim HJ,Fay MP,Feuer EJ,et al.Permutation tests for Joinpoint regression with applications to cancer rates[J].Statist Med,2000,19(3):335-351.
[8] 项永兵,张薇,高立峰,等.恶性肿瘤发病率的时间趋势分析方法[J].中华流行病学杂志,2004,25(2):173-177.
[9] 侯亚.运动-睡眠-心理三联护理干预对肺癌化疗患者癌因性疲乏的影响[J].齐鲁护理杂志,2014,20(23):51-52.
[10] 王宁,袁延楠,郑荣寿,等.中国恶性肿瘤城乡发病差异分析[J].中国肿瘤,2013,22(3):168-173.
[11] 董志伟,乔友林,李连弟,等.中国癌症控制策略研究报告[J].中国肿瘤,2002,11(5):250-260.
[12] 陈万青,郑荣寿,张思维,等.2003—2007年中国癌症发病分析[J].中国肿瘤,2012,21(3):161-170.
[13] 杨玲,李连弟,陈育德,等.中国 2000 年及 2005 年恶性肿瘤发病死亡的估计与预测[J].中国卫生统计,2005,22(4):218-221.
[14] Li W,Wang DZ,Zhang H,et al.Study on smoking attributed death and effects of smoking cessation in residents aged 35-79 years in Tianjin,2016[J].China J Epidemiol,2017,38(11):1533-1536.
[15] Barone E,Corrado A,Gemignani F,et al.Environmental risk factors for pancreatic cancer:anupdate [J].Archives of Toxicology,2016,90(11) :2617-2642.
[16] Keum N,Giovannucci E.Global burden of colorectal cancer:emergingtrends,riskfactorsandpreventionstrategies[J].Nat Rev Gastroenterol Hepatol,2019,16(12):713-732.
[17] Abnet CC,Arnold M,Wei WQ.Epidemiology of esophagealsquamous cell carcinoma [J].Gastroenterol,2018,154(2):360-373.
[18] Schottenfeld D,Fraumeni JF Jr.Cancer epidemiology and prevention[M].Oxford:Oxford University Press,2006.
PDF(878 KB)
