目的 分析安徽省肿瘤登记地区2010—2018年胃癌发病趋势变化情况,为制定胃癌防治措施提供基础数据。方法 将安徽省2010—2018年各肿瘤登记处上报数据按照地区(城乡)、性别分层计算胃癌发病率,分别计算中国人口标准化发病率(中标率)和世界人口标准化发病率(世标率),进行标化率的年度趋势分析。结果 2010—2018年安徽省肿瘤登记地区胃癌发病粗率为43.03/10万(男性60.45/10万,女性24.73/10万);安徽省城市肿瘤登记地区胃癌发病粗率为34.83/10万(男性48.25/10万,女性20.89/10万);安徽省农村肿瘤登记地区胃癌发病粗率为49.67/10万(男性70.23/10万,女性27.87/10万)。2010—2018年安徽省肿瘤登记地区胃癌发病中标率年度变化百分比(APC)=-5.33%(P<0.05),其中男性APC=-5.69%(P<0.05),女性APC=-4.27%(P<0.05);城市肿瘤登记地区胃癌发病中标率APC=-5.21%(P<0.05),其中男性APC=-5.50%(P<0.05),女性APC=-4.47%(P<0.05);农村肿瘤登记地区胃癌发病中标率APC=-6.05%(P<0.05),其中男性APC=-6.47%(P<0.05),女性APC=-4.64%(P<0.05)。结论 安徽省肿瘤登记地区胃癌发病呈现下降趋势,且下降幅度较大,但是还要重视农村地区特别是农村地区男性的胃癌预防和控制工作,推进胃癌早诊早治工作,提高早期胃癌的检出率,从而降低胃癌的发病率和死亡率。

Objective To analyze the trend changes of gastric cancer incidence in the cancer registration areas of Anhui Province from 2010 to 2018,and to provide basic data for the formulation of gastric cancer prevention and control measures. Methods The reported data from various cancer registration offices in Anhui Province from 2010 to 2018 were stratified by region (urban and rural) and gender to calculate the incidence rate of gastric cancer.The Chinese population standardized incidence rate and the world standardized incidence rate were calculated.The annual trend of standardized incidence rate was analyzed. Results The crude incidence rate of gastric cancer in the cancer registration areas of Anhui Province from 2010 to 2018 was 43.03/100 000,of which male 60.45/100 000 and female 24.73/100 000.The crude incidence rate of gastric cancer in the urban cancer registration areas of Anhui Province was 34.83/100 000,including 48.25/100 000 for male and 20.89/100 000 for females.The crude incidence rate of gastric cancer in the rural cancer registration areas of Anhui Province was 49.67/100 000,including 70.23/100 000 for males and 27.87/100 000 for females.The annual percentage change (APC) of the standardized incidence rate of gastric cancer in the Chinese population in the cancer registration areas of Anhui Province from 2010 to 2018 was-5.33% (P<0.05),with an APC of-5.69% (P<0.05) for males and-4.27% (P<0.05) for females.The APC of the standardized incidence rate of gastric cancer in the Chinese population in urban cancer registration areas was-5.21% (P<0.05),with an APC of-5.50% (P<0.05) for males and-4.47% (P<0.05) for females.The APC of the standardized incidence rate of gastric cancer in the Chinese population in rural cancer registration areas was-6.05% (P<0.05),with an APC of-6.47% (P<0.05) for males and-4.64% (P<0.05) for females. Conclusion The incidence of gastric cancer in the cancer registration areas of Anhui Province is decreasing,and the decrease is significant.However,attention should still be paid to the prevention and control of gastric cancer in rural areas,especially in rural males.Early diagnosis and treatment of gastric cancer should be promoted to improve the detection rate of early gastric cancer,so as to reduce the incidence and mortality of gastric cancer.