微生物特性对消毒效果影响研究现况

程文隽; 陈芳; 吴磊; 黄发源

doi:10.19837/j.cnki.ahyf.2023.04.013

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安徽预防医学杂志 ›› 2023, Vol. 29 ›› Issue (4) : 324-327. DOI: 10.19837/j.cnki.ahyf.2023.04.013

综述

微生物特性对消毒效果影响研究现况

程文隽, 陈芳, 吴磊, 黄发源

作者信息 +

Research progress on the influence of microbial characteristics on disinfection effectiveness

CHENG Wenjun, CHEN Fang, WU Lei, HUANG Fayuan

Author information +

文章历史 +

摘要

微生物在地球上广泛存在,与人类生活息息相关。2019年新型冠状病毒(SARS-Cov-2)引发公共卫生事件后,消毒剂使用量剧增,消毒效果评价也成为近年来的热门研究课题,了解不同微生物特性对消毒效果的影响至关重要。本文根据不同微生物的结构特征,分类阐述了原核微生物、真核微生物、非细胞型微生物对消毒效果的影响,同时,归纳总结了微生物不同生长时期、传代次数、自身机制等在消毒效果中可能存在的区别,为更好地选择消毒剂达到理想的消毒效果提供新思路。

Abstract

Microorganisms exist widely on earth and are closely related to human life.After the 2019 public health event caused by the novel coronavirus (SARS-Cov-2),the use of disinfectants has soared worldwide,and the evaluation of disinfection effect has become a hot research topic in recent years.Understanding the characteristics of different microorganisms is crucial to the disinfection effect.According to the structural characteristics of different types of microorganisms,this paper classified and expounded the influence of prokaryotic microorganisms,eukaryotic microorganisms and non-cellular microorganisms on the disinfection effect.At the same time,it summarized the possible differences of microorganisms in different growth periods,passage times,their own mechanisms,and so on in the disinfection effect,providing new ideas for better selection of disinfectants to achieve the desired disinfection effect.

导出引用

程文隽, 陈芳, 吴磊, 黄发源. 微生物特性对消毒效果影响研究现况[J]. 安徽预防医学杂志. 2023, 29(4): 324-327 https://doi.org/10.19837/j.cnki.ahyf.2023.04.013

CHENG Wenjun, CHEN Fang, WU Lei, HUANG Fayuan. Research progress on the influence of microbial characteristics on disinfection effectiveness[J]. Anhui Journal of Preventive Medicine. 2023, 29(4): 324-327 https://doi.org/10.19837/j.cnki.ahyf.2023.04.013

中图分类号： R187

参考文献

[1] 孙晓东,王丽洁,张奕,等.埃博拉病毒病流行病学进展 [J].中国口岸科学技术,2022,4(3):4-8.
[2] 冯晔囡,宋洋,王世文,等.全球新型冠状病毒变异株研究进展 [J].病毒学报,2021,37(3):695-711.
[3] 蔡鹏,殷建华,张宏伟.猴痘病原学、流行病学特征及其防控策略 [J].上海预防医学,2022,34(10):1044-1052.
[4] Marchesi JR,Ravel J.The vocabulary of microbiome research:a proposal [J].Microbiome,2015,3:31.
[5] 罗恩杰.病原生物学 [M].北京:科学出版社,2020:1-21.
[6] 刘荫武.细菌细胞壁的结构与革兰氏染色机制 [J].畜牧与兽医,1986,(5):204-206.
[7] 田靓,朱仁义,沈伟,等.酶类消毒剂应用研究进展 [J].中国消毒学杂志,2013,30(3):247-251.
[8] 李康.革兰氏阳性细菌细胞壁肽聚糖的超微结构研究 [D].山东:山东大学,2018.
[9] 黎金旭,林世红,林育.溶菌酶及其在抗菌消毒技术领域中的应用 [J].中国消毒学杂志,2010,27(3):326-328.
[10] 莫婷,刘马峰,程安春.部分革兰氏阴性菌脂多糖运输蛋白LptD的结构及功能研究进展 [J].微生物学通报,2017,44(1):217-224.
[11] Li XZ,Zhang L,Poole K.Role of the Multidrug efflux systems of pseudomonas aeruginosa in organic solvent tolerance [J].J Bacteriol,1998,180:2987-2991.
[12] 陈玉飞,帖金凤,蒙倩娜,等.两种过氧化氢消毒液对细菌芽孢杀灭效果的观察 [J].中国消毒学杂志,2019,36(11):804-807.
[13] Nakayama M,Hosoya K,Tomiyama D,et al.Method for rapid detection and identification of chaetomium and evaluation of resistance to peracetic acid [J].J Food Prot,2013,76(6):999-1005.
[14] 张荔,袁雪梅.臭氧消毒机在呼吸科床单位真菌消毒中的应用效果 [J].医疗装备,2020,33(3):54-55.
[15] 黄蔷薇,金茹,黄筱燕,等.床单位臭氧消毒机对血透室床单位消毒效果的研究 [J].中国消毒学杂志,2014,31(1):101-102.
[16] Ofstead CL,Heymann OL,Quick MR,et al.Residual moisture and waterborne pathogens inside flexible endoscopes:evidence from a multisite study of endoscope drying effectiveness [J].Am J Infect Control,2018,46(6):689-696.
[17] Wilson LA,Ahearn DG.Association of fungi with extended-wear soft contact lenses [J].Am J Ophthalmol,1986,101(4):434-436.
[18] Terleckyj B,Axler DA.Efficacy of disinfectants against fungi isolated from skin and nail infections [J].J Am Podiatr Med Assoc,1993,83(7):383-393.
[19] 王玲,徐燕.复方过氧化氢银离子消毒液对微生物杀灭效果的试验研究 [J].中国消毒学杂志,2021,38(11):810-813.
[20] 孟玲.病毒与消毒剂 [J].中国洗涤用品工业,2020(Z1):171-174.
[21] 朱昱敏,张亚雷,周雪飞,等.过氧乙酸在污水消毒中对病毒灭活的研究进展 [J].中国给水排水,2020,36(12):45-50.
[22] 南征,周妍妍,苏建荣,等.不同消毒方式对流感病毒RNA消除效果的研究 [J].中国消毒学杂志,2022,39(6):410-413.
[23] 何静芳,沈伟,马伟,等.噬菌体与病毒对常用消毒处理的抗力比较研究 [J].中国消毒学杂志,2007,24(2):118-121.
[24] 曹凤,任红,黄桂东,等.对数生长期酿酒酵母胞内代谢情况分析 [J].食品与发酵工业,2022,48(1):1-9.
[25] 马海乐,吴琼英,高梦祥,等.微生物不同生长期及介质参数对脉冲磁场杀菌效果的影响 [J].农业工程学报,2004,(5):215-217.
[26] 乌日娜,岳喜庆,张和平.干酪乳杆菌对数生长期与稳定期蛋白质组比较分析 [J].食品科学,2012,33(13):148-151.
[27] 芮期义,王新为,欧阳川,等.Vitek微生物分析仪测定传代的大肠杆菌生理生化变化 [J].解放军预防医学杂志,1994,(3):196-198.
[28] 张璐瑶,孟琳,颛清芮,等.基于微生物16SrRNA测序技术对ICR小鼠传代后肠道菌群变化的分析 [J].中国农业大学学报,2022,27(7):126-136.
[29] 刘玉莲.微波灭菌柜消毒效果影响因素研究 [J].中国消毒学杂志,2022,39(3):172-173+176.
[30] 张可玟,胡泓,陈刚.微生物消毒剂抗性机理 [J].生物化学与生物物理进展,2022,49(1):34-47.
[31] Donlan RM,Costerton JW.Biofilms:survival mechanisms of clinically relevant microorganisms [J].Clin Microbiol Rev,2002,15(2):167-193.
[32] 李祥,鲁辛辛.肺炎克雷伯菌对消毒剂抗性的研究进展 [J].临床检验杂志,2019,37(1):55-56.
[33] 陈琪,唐非.医院常见致病菌生物膜形成能力的研究进展 [J].中国消毒学杂志,2022,39(3):226-229.
[34] Surdeau N,Laurent-Maquin D,Bouthors S,et al.Sensitivity of bacterial biofilms and planktonic cells to a new antimicrobial agent,Oxsil 320N [J].J Hosp Infect,2006,62(4):487-493.
[35] Tettmann B,Dotsch A,Armant O,et al.Knockout of extracytoplasmic function sigma factor ECF-10 affects stress resistance and biofilm formation in pseudomonas putida KT2440 [J].Appl Environ Microbiol,2014,80(16):4911-4919.
[36] Vikram A,Bomberger JM,Bibby KJ.Efflux as a glutaraldehyde resistance mechanism in pseudomonas fluorescens and pseudomonas aeruginosa biofilms [J].Antimicrob Agents Chemother,2015,59(6):3433-3440.
[37] 王帅涛,高倩倩,成娟丽,等.铜绿假单胞菌生物被膜组成及其受群体感应系统和c-di-GMP调控的研究进展 [J].微生物学报,2021,61(5):1106-1122.
[38] Reichhardt C,Parrsek MR.Confocal laser scanning microscopy for analysis of pseudomonas aeruginosa biofilm architecture and matrix localization [J].Front Microbiol,2019,10:677.
[39] 王若卿,王怡,袁洛薇.高浓度消毒剂对再生水管道生物膜中微生物的影响 [J].中国给水排水,2016,32(5):14-17+22.
[40] 杭霞,缪刚刚,张雪.应用二喹啉甲酸法评价管腔器械清洗效果的研究 [J].中国消毒学杂志,2022,39(6):407-409.
[41] Shirshikova TV,Sierra-Bakhshi CG,Kamaletdinova LK,et al.The ABC-type efflux pump macAB Is involved in protection of serratia marcescens against aminoglycoside antibiotics,polymyxins,and oxidative stress[J].mSphere,2021,6(2):e00033-00021.
[42] Robin B,Nicol M,Le H,et al.MacAB-TolC contributes to the development of acinetobacter baumannii biofilm at the solid–liquid interface [J].Front Microbiol,2022,12.
[43] Du D,Wang-Kan X,Neuberger A,et al.Multidrug efflux pumps:structure,function and regulation [J].Nat Rev Microbiol,2018,16(9):523-539.
[44] Labreck PT,Bochi-Layec AC,Stanbro J,et al.Systematic analysis of efflux pump-mediated antiseptic resistance in staphylococcus aureus suggests a need for greater antiseptic stewardship.[J].mSphere,2020,5(1):e00959-00919.
[45] 侯盼飞,余九峰,周素芹.老年科鲍曼不动杆菌耐药性及外排泵基因研究 [J].实用临床医药杂志,2022,26(7):26028.
[46] Liffourrena AS,Lucchesi GI.Identification,cloning and biochemical characterization of pseudomonas putida A (ATCC 12633) monooxygenase enzyme necessary for the metabolism of tetradecyltrimethylammonium bromide [J].Appl Biochem Biotechnol,2014,173(2):552-561.
[47] Skovgaard S,Nielsen LN,Larsen MH,et al.Staphylococcus epidermidis isolated in 1965 are more susceptible to triclosan than current isolates [J].PLoS One,2013,8(4):e62197.
[48] Waldman P,Meseguer A,Lucas F,et al.Interaction of human enteric viruses with microbial compounds:Implication for virus persistence and disinfection treatments [J].Environ Sci Technol,2017,51(23):13633-13640.