目的 采用多频稳态诱发电位法探究客观听力学检查在职业性噪声聋诊断中的应用,以鉴别诊断职业性噪声聋。方法 对61例客观聋组、64例夸大聋组和35例正常听力组3组人员均行 0.5k Hz、1k Hz、2k Hz、4k Hz 共4个频率处的多频稳态诱发电位和纯音测试,并将测试结果进行方差分析、Pearson 相关分析、一元线性回归分析统计分析。结果 各频率多频稳态诱发电位反应阈与纯音测试听阈的相关系数在正常听力组依次为0.66 、0.85 、0.80 、0.73,在客观聋组依次为 0.83 、0.84 、0.90 、 0.78,而在夸大聋组依次为0.38 、 0.35 、0.50 、0.48,说明多频稳态诱发电位法作为客观听力测试可以鉴别伪聋或夸大性聋。结论 应用多频稳态诱发电位鉴别诊断职业性噪声聋是可行的,具有临床应用价值。

Objective To explore the application of objective audiological examination in the diagnosis of occupational noise deafness by multi-frequency steady-state evoked potential (MSEP) in order to differentiate and diagnose occupational noise deafness. Methods Multi-frequency steady-state evoked potentials and pure tones were measured at four frequencies (0.5k Hz, 1k Hz, 2k Hz,4k Hz) in 61 objective deafness, 64 exaggerated deafness and 35 cases of normal hearing. The results were analyzed by variance analysis, pearson correlation analysis and linear regression analysis. Results The correlation coefficients of response thresholds of MSEP and pure tone test thresholds were 0.66, 0.85, 0.80 and 0.73 in normal hearing group, 0.83, 0.84, 0.90 and 0.78 in objective deafness group, and 0.38, 0.35, 0.50 and 0.48 in exaggerated deafness group, respectively. This indicated that MSEP could be used as objective hearing test to identify pseudo deafness or exaggerated deafness. Conclusion Differential diagnosis of occupational noise deafness by MSEP is feasible and has clinical application value.