Objective To explore the characteristics and prevalence of school legal infectious diseases in Huaibei City. Methods In the Infectious Disease Report Information Management System,the data on the incidence of school legal infectious diseases in Huaibei City from 2016 to 2018 were collected,and the epidemic characteristics of school legal infectious diseases were analyzed by descriptive epidemiological analysis. Results From 2016 to 2018,there were 4246 cases of school legal infectious diseases in Huaibei City,accounting for 15.52% of the total reported cases of infectious diseases in Huaibei City.Among them,88 cases occurred in teachers,1 907 cases in primary and secondary school students and 251 cases in kindergartens.In February,the incidence was the lowest (151 cases),and in May,it was the highest (662 cases).Hand,foot and mouth disease mainly occured in kindergartens.Mumps and influenza mainly occured in primary and secondary schools. Conclusion Influenza,mumps and hand foot mouth disease were the main infectious diseases in schools in Huaibei City.Tuberculosis cases in teachers may pose a risk to the spread of tuberculosis in schools.