Objective To explore the crisis status and the influencing factors in psychiatric patients during COVID-19 epidemic. Methods Sixty inpatients who were admitted to psychiatric department of the hospital from December 2019 to March 2020 were enrolled as the research objects.According to the risk assessment results about presence or absence of violence, running away and self-abandonment, they were divided into crisis group (n=19) and non-crisis group (n=41).Crisis status and the influencing factors in psychiatric patients during COVID-19 epidemic were analyzed. Results Of the psychosis inpatients, there were 76.67% (46/60) with paranoid psychosis.The schizophrenia, mania, depression and other types of symptoms accounted for 5.00%, 3.33%, 5.00% and 10.00%, respectively.Univariate and multivariate analysis showed that monthly household income per capita less than 3,000 yuan, score of Hamilton Depression Scale (HAMD) higher than 13 points, score of Hamilton Anxiety Scale (HAMA) higher than 13 points, score of global assessment function scale (GAF) not higher than 50 points and score of short form 36 health survey (SF-36) not higher than 60 points were independent risk factors of crisis status (suicide, violence, running away) in psychosis inpatients(P=0.025、0.016、0.017、0.041、0.028).There were no significant differences between crisis group and non-crisis group in gender, age, occupation and disease course (P＞0.05). Conclusion During the epidemic of novel coronavirus pneumonia, the risk of psychiatric crisis such as violence, walking away and self abandoned has increased.Low level of social support and life care, and high score of negative emotion are risk factors of increasing crisis state, which can provide help for psychiatric department to formulate risk prevention measures.