Follow up detection of COVID-19 asymptomatic infection in close contacts

WANG Gong-fei; ZHA Tao; WANG Yi; WANG Fei

doi:10.19837/j.cnki.ahyf.2020.05.010

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Anhui Journal of Preventive Medicine ›› 2020, Vol. 26 ›› Issue (5) : 368-370. DOI: 10.19837/j.cnki.ahyf.2020.05.010

Follow up detection of COVID-19 asymptomatic infection in close contacts

WANG Gong-fei, ZHA Tao, WANG Yi, WANG Fei

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Abstract

Objective To track and detect close contacts with asymptomatic infection in a COVID-19 outbreak. Methods Multiple real-time RT-PCR with RNaseP internal amplification control combined with total serum antibody (colloidal gold) assay was used to detect multiple types of specimens from suspected cases and asymptomatic close contacts. Results 1 suspected COVID-19 case was positive for SARS-CoV-2 RNA on throat swabs and sputum specimens.2 of 318 asymptomatic close contacts were SARS-CoV-2 RNA positive and the remaining 316 were SARS-CoV-2 RNA negative in throat swabs,11 of these 316 were total antibody positive (2 of 11 were SARS-CoV-2 RNA positive in anal swabs). Conclusion Collection of multiple specimen types combined with detection of multiple methods is of great significance for tracking and detecting close contacts with SARS-CoV-2 asymptomatic infection.

Key words

COVID-19 / SARS-CoV-2 / Nucleic acid test / RT-PCR

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WANG Gong-fei, ZHA Tao, WANG Yi, WANG Fei. Follow up detection of COVID-19 asymptomatic infection in close contacts[J]. Anhui Journal of Preventive Medicine. 2020, 26(5): 368-370 https://doi.org/10.19837/j.cnki.ahyf.2020.05.010

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