Research Progress on the effect of maternal vitamin D level and its anabolism on fetal development

LING Yi-ke; PAN Yu-bo; BAI Meng-ru; GUI Yan-chao; ZHAO Yan-yan; LI Li

doi:10.19837/j.cnki.ahyf.2020.06.008

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Anhui Journal of Preventive Medicine ›› 2020, Vol. 26 ›› Issue (6) : 438-443. DOI: 10.19837/j.cnki.ahyf.2020.06.008

Research Progress on the effect of maternal vitamin D level and its anabolism on fetal development

LING Yi-ke^*, PAN Yu-bo, BAI Meng-ru, GUI Yan-chao, ZHAO Yan-yan, LI Li

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Abstract

Vitamin D,also known as calcified sterol,is a fat soluble vitamin and steroid.Vitamin D has the biological functions of maintaining calcium and phosphorus homeostasis,and promoting bone mineralization.Maternal vitamin D level affects fetal vitamin D level,which has a certain impact on the growth and development of pregnant women and fetus as well as the nutritional status of adults.Vitamin D deficiency in pregnancy is related to preeclampsia,gestational diabetes and bacterial vaginosis,and increases the risk of caesarean section.The relationship between vitamin D level and growth and development of fetus is reflected in bone development,congenital rickets,anthropometric indicators (head circumference,chest circumference,birth weight,etc.) and other non-bone diseases.To study the effect of maternal vitamin D level and its anabolism on fetal development is of practical significance to meet the nutritional needs of pregnant women,guide the diet of pregnant women and improve the development of offspring.

Key words

Pregnant women / Vitamin D / Fetus / Development / Population quality / Review

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LING Yi-ke, PAN Yu-bo, BAI Meng-ru, GUI Yan-chao, ZHAO Yan-yan, LI Li. Research Progress on the effect of maternal vitamin D level and its anabolism on fetal development[J]. Anhui Journal of Preventive Medicine. 2020, 26(6): 438-443 https://doi.org/10.19837/j.cnki.ahyf.2020.06.008

References

[1] Turer CB,Hua L,Glenn F.Prevalence of vitamin D deficiency among overweight and obese US children[J].Pediatrics,2013,131(1): 152-161.
[2] Josefson JL,Feingless J,Rademaker AW,et al.Maternal obesity and vitamin D sufficiency are associated with cord blood vitamin D insufficiency[J].J Clin Endocrinol Metab,2013,98(1): 114-119.
[3] Rodríguez-Dehli AC,Riaño GI,Fernández-Somoano A,et al.Prevalence of vitamin d deficiency and insuffiency and associated factors in pregnant women of northern Spain[J].Nutricion Hospitalaria,2015,31(4): 1633-1640.
[4] Earthman CP,Beckman LM,Masodkar K,et al.The link between obesity and low circulating 25-hydroxyvitamin D concentrations: considerations and implications[J].Int J Obes (Lond),2012,36(3): 387-396.
[5] Jäpelt RB,Jakobsen J.Vitamin D in plants: a review of occurrence,analysis,and biosynthesis[J].Frontiers in Plant Science,2013,4(2): 136.
[6] Pospechova K,Rozehnal V,Stejskalova L,et al.Expression and activity of vitamin D receptor in the human placenta and in choriocarcinoma BeWo and JEG-3 cell lines[J].Molecular & Cellular Endocrinology,2009,299(2): 178-187.
[7] Claudio M,Francesca U,Elena G,et al.1α,25-dihydroxycholecalciferol induces nitric oxide production in cultured endothelial cells[J].Cellular Physiology & Biochemistry International Journal of Experimental Cellular Physiology Biochemistry & Pharmacology,2011,27(6): 661-668.
[8] Boris N,Mandy S,Kiat NH,et al.Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface[J].Journal of Biological Chemistry,2009,284(22): 14838-48.
[9] Nesterova G,Malicdan MC,Yasuda K,et al.1,25-(OH)2D-24 Hydroxylase (CYP24A1) Deficiency as a Cause of Nephrolithiasis[J].Clin J Am Soc Nephrol,2013,8(4): 649-657.
[10] Brannon PM.Vitamin D and adverse pregnancy outcomes: beyond bone health and growth[J].Proc Nutr Soc,2012,71(2): 205-212.
[11] Grundmann M,Von VF.Vitamin D - roles in women's reproductive health?[J].Reproductive Biology & Endocrinology,2011,9(1): 1-12.
[12] Shin JS,Choi MY,Longtine MS,et al.Vitamin D effects on pregnancy and the placenta[J].Placenta,2010,31(12): 1027-1034.
[13] Seamans KM,Cashman KD.Existing and potentially novel functional markers of vitamin D status: a systematic review[J].Am J Clin Nutr,2009,89(6):1997-2008.
[14] Javaid MK,Crozier SR,Harvey NC,et al.Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study[J].Lancet (London,England),2006,9504(367):36-43.
[15] Vandevijvere S,Amsalkhir S,Oyen HV,et al.High Prevalence of Vitamin D Deficiency in Pregnant Women: A National Cross-Sectional Survey[J].Plos One,2012,7(8):e43868.
[16] Lisa MB.Vitamin D may be a link to black-white disparities in adverse birth outcomes[J].Obstetrical & gynecological survey,2010,4(65):.
[17] Dror DK,Allen LH.Vitamin D inadequacy in pregnancy: biology,outcomes,and interventions[J].Nutrition Reviews,68(8): 465-477.
[18] Fuller KE.Low birth-weight infants: the continuing ethnic disparity and the interaction of biology and environment[J].Ethnicity & Disease,2000,10(3): 432.
[19] Meer IM,Van Der,Karamali NS,Boeke AJP,et al.High prevalence of vitamin D deficiency in pregnant non-Western women in The Hague,Netherlands[J].American Journal of Clinical Nutrition,2006,84(2): 350-353.
[20] Hossein A.Vitamin D for Health: A Global Perspective - Mayo Clinic Proceedings[J].Mayo Clinic Proceedings Mayo Clinic,2013,88(7): 720-755.
[21] Wielders JP,van Dormaël PD,Eskes PF,et al.Severe vitamin-D deficiency in more than half of the immigrant pregnant women of non-western origin and their newborns[J].Nederlands Tijdschrift Voor Geneeskunde,2006,150(9): 495.
[22] Baker PN,Wheeler SJ,Sanders TA,et al.A prospective study of micronutrient status in adolescent pregnancy[J].American Journal of Clinical Nutrition,2009,89(4): 1114-1124.
[23] 胡贻椿,陈竞,李敏,等.2010—2012年中国城市孕妇贫血及维生素A、维生素D营养状况[J].中华预防医学杂志,2017,51(2): 125-131.
[24] Grant CC,Stewart AW,Scragg R,et al.Vitamin D During Pregnancy and Infancy and Infant Serum 25-Hydroxyvitamin D Concentration[J].Pediatrics,2014,133(1): e143-e153.
[25] Urrutia RP,Thorp JM.Vitamin D in pregnancy: current concepts[J].Curr Opin Obstet Gynecol,2012,24(2): 57-64.
[26] Dawodu A,Wagner CL.Mother-child vitamin D deficiency: an international perspective[J].Archives of Disease in Childhood,2007,92(9): 737-740.
[27] Thacher TD,Fischer PR,Strand MA,et al.Nutritional rickets around the world: causes and future directions[J].Annals of Tropical Paediatrics,2006,26(1): 1-16.
[28] Zittermann A,Prokop S.The role of vitamin D for cardiovascular disease and overall mortality[J].Advances in Experimental Medicine & Biology,2014,810:106-19.
[29] Pludowski P,Holick MF,Pilz S,et al.Vitamin D effects on musculoskeletal health,immunity,autoimmunity,cardiovascular disease,cancer,fertility,pregnancy,dementia and mortality—A review of recent evidence[J].Autoimmunity Reviews,2013,12(10): 976-989.
[30] Giovanna M,Joanna M,Chantal M,et al.Mechanisms in endocrinology: vitamin D as a potential contributor in endocrine health and disease[J].European Journal of Endocrinology,2014,171(3): 101-110.
[31] Brehm JM,Celedón JC,Soto-Quiros ME,et al.Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica[J].American Journal of Respiratory & Critical Care Medicine,2009,179(9): 765.
[32] Samuel L,Borrell LN.The effect of body mass index on optimal vitamin D status in U.S.adults: The National Health and Nutrition Examination Survey 2001-2006[J].Annals of Epidemiology,23(7): 409-414.
[33] Wortsman J,Matsuoka LY,Chen TC,et al.Decreased bioavailability of vitamin D in obesity[J].American Journal of Clinical Nutrition,2000,72(3): 690-693.
[34] Pramyothin P,Biancuzzo RM,Lu Z,et al.Vitamin D in Adipose Tissue and Serum 25-Hydroxyvitamin D After Roux-en-Y Gastric Bypass[J].Obesity,2011,19(11): 2228-2234.
[35] Roizen JD,Long C,Casella A,et al.Obesity Decreases Hepatic 25-Hydroxylase Activity Causing Low Serum 25-Hydroxyvitamin D[J].J Bone Miner Res,2019,34(6): 1068-1073.
[36] Kovacs CS.Vitamin D in pregnancy and lactation: maternal,fetal,and neonatal outcomes from human and animal studies[J].American Journal of Clinical Nutrition,2008,88(2): 520S.
[37] Agarwal S,Kovilam O,Agrawal DK.Vitamin D and its impact on maternal-fetal outcomes in pregnancy: A critical review[J].Crit Rev Food Sci Nutr,2016,58(6):755-769.
[38] Ajb E,Dockery K,Mughal MZ,et al.Vitamin D status of White pregnant women and infants at birth and 4 months in North West England: A cohort study[J].Maternal & Child Nutrition,2017,e12453.
[39] Bishop N,Fewtrell M,Harvey NC.Chapter 24 - Metabolic Bone Disease in the Neonatal Period and its Later Sequelae[J].Pediatric Bone,2012,655-677.
[40] Pramila K,Vinita D,Anjoo A,et al.Effect of vitamin D supplementation during pregnancy on neonatal mineral homeostasis and anthropometry of the newborn and infant[J].Br J Nutr,2012,108(6): 1052-1058.
[41] Brooke OG,Brown IR,Bone CD,et al.Vitamin D supplements in pregnant Asian women: effects on calcium status and fetal growth[J].British Medical Journal,1980,280(6216): 751-754.
[42] Cullers A,King J,Van L,et al.Effect of prenatal calcium supplementation on bone during pregnancy and 1 y postpartum[J].The American journal of clinical nutrition,2019,109(1): 197-206.
[43] Nazli H,Kanani FH,Shabana R,et al.Obstetric and neonatal outcomes of maternal vitamin D supplementation: results of an open-label,randomized controlled trial of antenatal vitamin D supplementation in Pakistani women[J].J Clin Endocrinol Metab,2014,99(7): 2448-2455.
[44] Morales E,Rodriguez A,Valvi D,et al.Deficit of vitamin D in pregnancy and growth and overweight in the offspring[J].International Journal of Obesity,2015,39(1): 61.
[45] Yu C,Sykes LM,Teoh T,et al.Vitamin D deficiency and supplementation during pregnancy[J].Clinical Endocrinology,2010,70(5): 685-690.
[46] De-Regil LM,Palacios C,Lombardo LK,et al.Vitamin D supplementation for women during pregnancy[M].2016.
[47] Bogazzi F,Rossi G,Lombardi M,et al.Vitamin D status may contribute to serum insulin-like growth factor I concentrations in healthy subjects[J].Journal of Endocrinological Investigation,2011,34(8): e200-e203.
[48] Pietro A,Andrea G,Mara B,et al.Vitamin D increases circulating IGF1 in adults: potential implication for the treatment of GH deficiency[J].European Journal of Endocrinology,2013,169(6): 767-772.
[49] Holick MF.Vitamin D: importance in the prevention of cancers,type 1 diabetes,heart disease,and osteoporosis[J].American Journal of Clinical Nutrition,2004,79(3): 362-371.
[50] Roth DE,Nandita P,Abdullah AM,et al.Maternal Vitamin D3 Supplementation during the Third Trimester of Pregnancy: Effects on Infant Growth in a Longitudinal Follow-Up Study in Bangladesh[J].Journal of Pediatrics,2013,163(6): 1605-1611+3.
[51] Goyal R,Zhang L,Blood AB,et al.Characterization of an animal model of pregnancy-induced vitamin D deficiency due to metabolic gene dysregulation[J].American Journal of Physiology Endocrinology & Metabolism,2014,306(3): E256.
[52] Hyppönen E,Läärä E,Reunanen A,et al.Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study[J].Lancet,2001,358(9292): 1500-1503.
[53] Josefson JL,Reisetter A,Scholtens DM,et al.Maternal BMI Associations with Maternal and Cord Blood Vitamin D Levels in a North American Subset of Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Participants[J].PLoS One,2016,11(3): e0150221.
[54] Crozier SR,Harvey NC,Inskip HM,et al.Maternal vitamin D status in pregnancy is associated with adiposity in the offspring: findings from the Southampton Women's Survey[J].American Journal of Clinical Nutrition,2012,96(1): 57-63.
[55] Krishnaveni GV,Veena SR,Winder NR,et al.Maternal vitamin D status during pregnancy and body composition and cardiovascular risk markers in Indian children: the Mysore Parthenon Study[J].American Journal of Clinical Nutrition,2011,93(3): 628-635.
[56] Javaid MK,Crozier SR,Harvey NC,et al.Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study[J].Lancet,2006,367(9504): 36-43.
[57] Karras SN,Anagnostis P,Naughton D,et al.Vitamin D during pregnancy: why observational studies suggest deficiency and interventional studies show no improvement in clinical outcomes? A narrative review[J].Journal of Endocrinological Investigation,2015,38(12): 1265-1275.
[58] Harvey NC,Christopher H,Georgia N,et al.Vitamin D supplementation in pregnancy: a systematic review[J].Health Technol Assess,2014,18(45):1-190.
[59] Gale CR,Robinson SM,Harvey NC,et al.Maternal vitamin D status during pregnancy and child outcomes[J].Eur J Clin Nutr,2008,62(1): 68-77.
[60] Adekunle D,Wagner CL.Mother-child vitamin D deficiency: an international perspective[J].Archives of Disease in Childhood,2007,92(9): 737-740.
[61] Martini LA,Eliseu V,Marchioni DML,et al.Prevalence and correlates of calcium and vitamin D status adequacy in adolescents,adults,and elderly from the Health Survey-Sao Paulo[J].Nutrition,2013,29(6): 845-850.
[62] Oliveira RMS,Novaes JF,Azeredo LM,et al.Association of vitamin D insufficiency with adiposity and metabolic disorders in Brazilian adolescents[J].Public Health Nutrition,2014,17(4): 787-794.
[63] Holmes VA,Barnes MS,H Denis A,et al.Vitamin D deficiency and insufficiency in pregnant women: a longitudinal study[J].Br J Nutr,2009,102(6): 876-881.
[64] Ustuner Isik,Keskin H Levent,Tas Emre Erdem,et al.Maternal serum 25(OH)D levels in the third trimester of pregnancy during the winter season[J].Journal of Maternal-Fetal Medicine,2011,24(12): 1421-1426.
[65] Eggemoen AR,Falk RS,Knutsen KV,et al.Vitamin D deficiency and supplementation in pregnancy in a multiethnic population-based cohort[J].Bmc Pregnancy & Childbirth,2016,16(1): 7.