Objective To analyze the characteristics of secondary infection with newbunyavirus in patients with fever and thrombocytopenia syndrome in Xinyang City. Methods The data of the same patient at different time were collected and analyzed.Result Two new bunyavirus nucleic acid tests were positive.The first onset of the patient had a long fever duration,severe clinical condition,high viral load and long course of disease;while the second onset of the patient had a short fever course,mild symptoms,low viral load and rapid recovery,indicating that the body had certain immunity to SFTSV;but the serum ALT,AST,LDH and CK were significantly higher than those of the first onset. Conclusion The repeated infection of the new bunyavirus causes the body to produce immunity with the participation of allergy,which is very similar to Koch phenomenon.The time interval between the two infections of the patient is less than 2 years,which indicates that the SFTSV may have mutation or multiple serotypes,or the SFTSV infection can not obtain lasting immunity.
Key words
newbunyavirus /
repeated infection /
clinical characteristics /
emerging infectious diseases
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