Objective To analyze the epidemiological characteristics of COVID-19 in Anqing City in 2020 and explore the causes of the epidemic. Methods Descriptive epidemiological method was used to analyze the infection sources and clustering characteristics of COVID-19 confirmed cases. Results In 2020,83 COVID-19 confirmed cases were found in Anqing City,including 53 imported cases and 30 local infections.The epidemic situation in Anqing City was first in the period of rapid increase of imported cases,then turned into a peak where imported cases and local infections coexist.After February 1st,the epidemic was slowly decreasing.In the rising period of the epidemic,76.92% of suspected cases were diagnosed as confirmed cases,50.00% in the peak period of the epidemic and 34.00% in the declining period of the epidemic.The difference was statistically significant.The incidence of close contact patients accounted for 4.43%,2.58% and 0.59% respectively in the rising,peak and declining periods of the epidemic situation,and the difference was statistically significant.The age of the patients was mainly between 20 and 60 years old,and the age of Wuhan imported cases was lower than that of local cases,the difference was significant.The occupation was mainly farmers,accounting for 36.14%.The clustered epidemic was mainly spread within the family,accounting for 94.12% (16/17). Conclusion COVID-19 epidemic in Anqing City is mainly imported cases and clusters in families.The clustering epidemic mainly occurred at the peak of the epidemic.In the early stage of the epidemic,the incidence of close contacts was higher.