Combined with the actual tasks and characteristics of emergency command and disposal of various public health emergencies,a scientific and professional framework layout of "four centers" and "nine in one" functions of municipal health emergency operation center was formed,the task bearing of 16 health emergency function parts in four categories was accurately described,and the work process of key health emergency function parts was clarified.It has solved the problem of "how to design,how to build and how to use" of the health emergency operation center,and has become a comprehensive,professional,whole process and multi-functional municipal health emergency operation center,which has been tested,improved and played an important role in actual combat,drills and practical applications.