Analysis of thecauses of varicella outbreak in a boarding school in Western Anhui Province

WANG Yao; QIN Wei; XU Xiao-kang; MENG Xiang-mei; GONG Peng-fei; XIA Feng

doi:10.19837/j.cnki.ahyf.2022.01.008

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Anhui Journal of Preventive Medicine ›› 2022, Vol. 28 ›› Issue (1) : 35-38. DOI: 10.19837/j.cnki.ahyf.2022.01.008

Analysis of thecauses of varicella outbreak in a boarding school in Western Anhui Province

WANG Yao^*, QIN Wei, XU Xiao-kang, MENG Xiang-mei, GONG Peng-fei, XIA Feng

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Abstract

Objective To analyze the causes of varicella outbreak in a boarding school in western Anhui,and to evaluate the protective effect of varicella vaccine. Methods An on-site survey and descriptive epidemiological analysis on students of the school were conducted by developing a uniform questionnaire and case definition.A retrospective cohort study was used to evaluate the protective effect of varicella vaccine. Results A total of 40 varicella cases were reported in schools,with an attack rate of 5.33% (40/750),a vaccination rate of 52.74% (279/529),and a breakthrough cases rate of 3.58% (10/279).Multivariate Logistic regression analyses showed that the risk of boarding students was 4.62 times higher than that of day students (OR=4.62,95%CI:2.142-9.993).The total protective effect of one-dose varicella vaccine was 69.35% (95%CI:35.804-85.403)within the protective effect on moderate and severe varicella was 83.84% (95%CI:26.403-96.502).The protective effect was 100% within 5 years and the protective effect decreased to 63.38% (95%CI:23.104-82.603) over 5 years. Conclusion The occurrence and spread of this epidemic are related to the low vaccination rate of varicella vaccine,poor protection effect of one-dose varicella vaccine,poor management of boarding students and irregular isolation of cases.

Key words

Varicella / Vaccination / Protective effect of vaccine / Outbreak / Field epidemiology

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WANG Yao, QIN Wei, XU Xiao-kang, MENG Xiang-mei, GONG Peng-fei, XIA Feng. Analysis of thecauses of varicella outbreak in a boarding school in Western Anhui Province[J]. Anhui Journal of Preventive Medicine. 2022, 28(1): 35-38 https://doi.org/10.19837/j.cnki.ahyf.2022.01.008

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