Objective To understand the repeated reporting of hepatitis C in Wuhu City and analyze the factors affecting the repeated reporting. Methods The reported cases of hepatitis C in Wuhu City from 2017 to 2021 were collected from the infectious disease surveillance system of the China Disease Prevention and Control Information System.The repeat reporting rate of hepatitis C cases was calculated by checking whether the reported cases were repeatedly reported according to the patient's ID number or patient's name,gender,population classification,disease name,date of birth,and current address. Results A total of 5 317 cases of hepatitis C were reported by healthcare institutions from 2017 to 2021,and 928 cases were repeatedly reported,with a repeat reporting rate of 17.45 %.A total of 240 cases were repeatedly reported in the year,with an average annual rate of 4.5%.There was no significant difference in the repetition rate between years (χ²=1.036,P>0.05).688 cases were repeatedly reported between years,with a repeat reporting rate of 13.55%.With the increase of age,the repeat reporting rate showed an upward trend.There was a statistically significant difference in the repeat reporting rate among the different age groups (χ²=68.89,P<0.05).The repeat reporting rate,in descending order,was at the prefectural and municipal levels (19.14%),provincial level (17.69%),township and below (16.56%),and county and district levels (15.21%). Conclusion There is repeated reporting of Wuhu City hepatitis C cases,mainly in the form of repeated reporting by provincial and municipal medical institutions and re-reporting across years.