Objective To analyze the effects of different walking interventions on body mass index (BMI),waist circumference of occupational population,and to provide the basis for scientific walking. Methods A total of 12 493 people aged 18 to 60 years old who participated in the Healthy Walking Incentive Program in Anhui Province from 2017 to 2021 were selected as the research subjects.A uniform pedometer,height tester and waist circumference were used to measure the walking behavior,height,weight and waist circumference of the study subject.The quantitative relationship between walking behavior and BMI and waist circumference was analyzed by generalized linear model (GLM).A three categorical ordered cumulative logistic regression model was used to analyze the influence of walking on overweight,obesity and central obesity. Results During the five years,a total of 12 493 subjects completed walking activities in line with the Healthy Walking Incentive Program in Anhui Province and finished all measurements,including 5 956 males and 6 537 females,with a mean age of (41.15± 9.86) years.After 100 days of walking intervention,participants showed reductions in outcomes related to overweight or obesity.BMI and waist circumference decreased by 0.23 kg/m² and 1.95 cm with each increase of 1 000 steps per day,and the risk of developing obesity decreased by 4.20% of that before the intervention.Compared to the intensive walking rate non-100% group,BMI and waist circumference of the group with 100% intensive walking decreased by 0.19 kg/m² and 0.32 cm,and the risk of developing obesity decreased by 38.80%.Compared with the non-100% group,BMI and waist circumference of the group that completed 100% exercise prescription decreased by 0.19 kg/m² and 0.26 cm,and the risk of developing toward overweight and obesity decreased by 16.70% and 24.30%,respectively.The BMI and waist circumference of the continuous ten thousand steps for 100 days group decreased by 0.11 kg/m² and 0.37 cm than those of the ten thousand consecutive steps less than 100 days group,and the risk of developing obesity decreased by 25.20%. Conclusion Walking intervention can reduce BMI and waist circumference of occupational population,improve overweight,obesity and central obesity,and has a positive effect on the prevention of chronic non-communicable diseases.