Objective To explore the risk factors of gastric cancer patients in key areas of the Huaihe River Basin,and to provide a basis for the primary prevention and control of gastric cancer in the Huaihe River Basin. Methods New cases of gastric cancer with a tumor diagnosis ICD-10 code of C16 between January 1,2020 and July 31,2021 were selected from the local regional (county) cancer registry system as the case group.In the same region,same gender,no previous history of malignancy,and age ±5 years were selected as the control group according to the 1:2 matching principle.Questionnaires and body measurements were administered to both groups.A total of 240 gastric cancer cases and 480 control cases were included.Risk factors of gastric cancer were analyzed by logistic regression using SAS. Results The results of multivariate logistic regression analysis showed that salty taste in diet (OR=2.161,95%CI:1.141-4.095),preference for spicy food (OR=1.773,95%CI:1.057-2.975),exposure to second-hand smoke (OR=1.963,95%CI:1.168-3.299),frequent anger (OR=8.704,95%CI:3.582-21.147) and history of digestive disorders (OR=2.302,95%CI:1.329-3.988) were risk factors for the development of gastric cancer.However,BMI (OR=0.697,95%CI:0.639-0.761),high literacy (OR=0.454,95%CI:0.248-0.830) and daily water intake ≥1 500 mL (OR=0.443,95%CI: 0.217-0.906) were negatively associated with the occurrence of gastric cancer. Conclusion The development of gastric cancer is associated with dietary habits,second-hand smoke exposure,personality and emotional characteristics,and history of digestive system diseases.Awareness of cancer prevention and control among the population,health education and behavioral guidance should be further strengthened to control cancer risk factors and reduce the risk of gastric cancer.
Key words
Gastric cancer /
Case-control study /
Risk factor /
Multifactor analysis
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