Analysis of the pathogenic spectrum of diarrhea in children in a district of Beijing City

KANG Ying; HE Mu; QIAO Shengxin; YAN Aixia; WANG Yanbo; ZHAO Yu; JING Hongbo; LI Ying

doi:10.19837/j.cnki.ahyf.2024.01.015

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Anhui Journal of Preventive Medicine ›› 2024, Vol. 30 ›› Issue (1) : 66-70. DOI: 10.19837/j.cnki.ahyf.2024.01.015

Disease Control

Analysis of the pathogenic spectrum of diarrhea in children in a district of Beijing City

KANG Ying¹, HE Mu¹, QIAO Shengxin², YAN Aixia¹, WANG Yanbo¹, ZHAO Yu¹, JING Hongbo¹, LI Ying¹

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Abstract

Objective To analyze the pathogenic spectrum of infectious diarrhea in children in a certain district of Beijing City,so as to provide reference for scientific prevention and control of children's infectious diarrhea. Methods Basic information and fecal samples of children with infectious diarrhea in a certain district of Beijing City from December 2021 to November 2022 were collected.The nucleic acids of 12 common bacteria and 3 viruses that caused diarrhea were detected by fluorescent PCR.Pathogenic spectrum was constructed and epidemic characteristics were analyzed. Results A total of 200 specimens of infectious diarrhea in children were collected,with a total pathogen detection rate of 35.00% (70/200).The detection rate of bacteria was 26.00% (52/200),with the top three detection rates being Escherichia coli (12.50%,25/200),Salmonella (9.00%,18/200),and Vibrio parahaemolyticus (5.50%,11/200),respectively.The virus detection rate was 10.50% (21/200),with rotavirus and norovirus detection rates of 4.00% (8/200) and 6.50% (13/200),respectively.In mixed infection,the detection rate of mixed infection of two bacteria was 5.00% (10/200),and the detection rate of mixed infection of one bacteria and one virus was 1.50% (3/200).There was statistically significant differences in the detection rate of bacterial pathogens (χ²=16.225,P=0.001) and viruses (χ²=35.184,P<0.001) in different seasons. Conclusion Diarrhoeal Escherichia coli,Salmonella,Vibrio parahaemolyticus,rotavirus,and norovirus have a high epidemic intensity in children with infectious diarrhea in a district of Beijing City.The coinfection of rotavirus,Salmonella and Vibrio parahaemolyticus with other bacterial pathogens should be given attention in children's diarrhea.

Key words

Infectious diarrhea in children / Pathogenic spectrum / Fluorescent PCR

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KANG Ying, HE Mu, QIAO Shengxin, YAN Aixia, WANG Yanbo, ZHAO Yu, JING Hongbo, LI Ying. Analysis of the pathogenic spectrum of diarrhea in children in a district of Beijing City[J]. Anhui Journal of Preventive Medicine. 2024, 30(1): 66-70 https://doi.org/10.19837/j.cnki.ahyf.2024.01.015

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