Objective To analyze the epidemiological characteristics of gonorrhea in Wuhu City from 2015 to 2022,and provide a basis for effective prevention and treatment measures. Methods Excel and SPSS 21.0 were used to analyze the data of gonorrhea cases reported in Wuhu from 2015 to 2022. Results From 2015 to 2022,a total of 2 687 cases of gonorrhea were reported in Wuhu City,and the reported incidence rate increased from 7.37/100 000 in 2015 to 9.26/100 000 in 2022,showing an overall upward trend(χ²_trend=10.080,P=0.001).The gender ratio between men and women was 5.96∶1,decreasing from 10.67∶1 in 2015 to 3.99∶1 in 2022,with a general downward trend (χ²_trend=10.760,P=0.001).78.04% of cases were concentrated in the age group of 15-39 year old.The incidence rate reported by the 15-19 age group (χ²_trend=141.451,P<0.001) and the 20-24 age group (χ²_trend=71.469,P<0.001) showed an upward trend.The peak age of onset of gonorrhea in males and females had shifted forward,showing a younger trend.The top three occupations were household and unemployed (38.56%),farmers(15.41%) and business services(14.18%),respectively. Conclusion The reported incidence rate of gonorrhea in Wuhu City is on the rise.It is necessary to extensively carry out gonorrhea related publicity activities and improve the management of gonorrhea diagnosis reports.