Objective To analyze the incidence trend and epidemiological characteristics of statutory reporting intestinal infectious diseases in Qiandongnan Prefecture from 2013 to 2022,providing data reference for prevention and control. Methods Descriptive analysis was used to analyze the incidence of statutory reporting intestinal infectious diseases in Qiandongnan Prefecture from 2013 to 2022,trend Chi- square test was followed to determine the overall incidence trend. Results In total,42 790 cases of statutory reporting intestinal infectious diseases were reported in Qiandongnan Prefecture from 2013 to 2022,average annual incidence was 120.28/100 000,differences in morbidity between years had statistical significance (χ²=2 355.372,P<0.001),suggesting a decline in overall incidence rate (χ²_trend=1 402.325,P<0.001).The reported cases mainly included hand-foot-mouth disease,other infectious diarrhea diseases,and dysentery,with a total of 39 895 reported cases,accounting for 93.23% of the total reported cases of legally stipulated reporting intestinal infectious diseases.The peak period of diseases was from March to July.In 42 790 cases,there were 26 591 males and 16 199 females,with a sex ratio of 1.64∶1.There was a statistically significant difference in the incidence rate between males and females (χ²=1 739.735,P<0.001).Cases reported in all age groups,0-4 age group reporting the most cases,with 31 120 cases accounting for 72.73%,followed by the 5-9 age group with 2 712 cases accounting for 6.34%. Conclusion Qiandongnan Prefecture reported an overall downward trend in legal intestinal infectious diseases,with a peak epidemic in summer,mainly among children in 0-4 age group.