Objective To analyze the trend and regional differences of various health supportive environment construction levels in Anhui Province’s China Healthy Lifestyle for All campaign from 2012 to 2022 ,and provide reference for evaluating the effectiveness of health supportive environment construction. Methods Information Management System of China Healthy Lifestyle for All was used for collecting construction data of various kinds of health supportive environment in Anhui Province from 2012 to 2022.Excel 2019 and SAS 9.4 were applied for data processing and analyzing,descriptive analysis method was used to describe the structure and distribution of health supportive environments. Results From 2012 to 2022,a total of 3 942 health supportive environments were established in Anhui Province,including 913 healthy families,658 healthy cabins,652 healthy communities,414 healthy units,352 health promoting schools,245 healthy trails,222 healthy canteens,200 healthy restaurants,176 healthy theme parks,45 healthy blocks/healthy streets and 3 healthy markets.There were differences in the level of creating healthy supportive environments among cities.The median number of health supportive environments was 171,the maximum number was 1 028,and the minimum number was 64. Conclusion The cumulative number of health supportive environments in Anhui Province showed an upward trend year by year,but there are differences in the number of new additions in different years,and the construction level of different types of health supportive environments also varies.Also,the construction level of health supportive environments in different cities is unbalanced and significantly differentiated.