Objective To analyze the epidemiological characteristics of the incidence and death of severe fever with thrombocytopenia syndrome (SFTS) in Huanggang of Hubei Province,and to provide reference for the prevention and control of SFTS. Methods The data of SFTS in Huanggang from 2011 to 2023 were collected and analyzed by descriptive epidemiological method. Results From 2011 to 2023,a total of 2 786 SFTS cases were reported from 109 towns in 10 Counties (Cities,Districts) in Huanggang,with an average annual incidence rate of 3.46/100 000.A total of 84 deaths were reported,with an average annual mortality rate of 0.10/100 000 and a fatality rate of 3.02%.The average annual incidence rate from 2011 to 2023 showed an upward trend,followed by a slight decline and leveling off,and then continued to rise (χ${}_{trend}^{2}$ =437.845,P<0.001).While the average annual mortality rate (χ${}_{trend}^{2}$=34.303,P<0.001) and the average annual fatality rate (χ${}_{trend}^{2}$=99.389,P<0.001) showed a downward trend,but there was a small rebound in 2017 and 2021.The cases were concentrated in Macheng City,Hong'an County,Yingshan County and Luotian County,which were connected to the north of Huanggang,accounting for 89.23% (2 486/2 786) of the cases,and the townships involved expanded from 57 townships in 2011 to 80 townships in 2023.The results of global spatial autocorrelation analysis and local hot and cold spot analysis showed that the incidence of SFTS in Huanggang had a certain spatial and temporal clustering.Three clusters of outbreaks in Huanggang were all related to the high possibility of infection caused by blood contact or other close contact with patients in the process of handling patients' funerals. Conclusion The incidence of SFTS in Huanggang showed an increasing and spreading trend,and the fatality rate showed an overall decreasing trend.The incidence of SFTS showed a certain spatial and temporal clustering.