Objective To understand the epidemic characteristics and trends of resident injury deaths in Jiaozuo City,Henan Province from 2019 to 2023,and to provide scientific basis for injury prevention and control. Methods The data of injury death were derived from Chinese Disease Prevention and Control System-Population Death Registration Information Management System.Death cases with death time from January 1,2019 to December 31,2023 and household registration address of Jiaozuo City selected.The injury death rate,standardized mortality rate and component ratio were calculated by Excel 2003 and SPSS 27.0,and annual percentage change (APC) was calculated by using Joinpoint Regression 5.2.0.0 software. Results From 2019 to 2023,the average injury mortality rate of Jiaozuo residents was 21.94/100 000 (standardized mortality rate 20.25/100 000).The average injury mortality rate was 30.93/100 000 for males,and 12.62/100 000 for females,the difference was statistically significant (χ²= 16.215,P<0.001).The injury mortality rate of the whole population of Jiaozuo showed a decreasing trend from 2019 to 2023 (APC=-3.10%,P<0.001).The top 5 causes of injury deaths in the whole population were transportation accident (death rate 10.90/100 000),unintentional fall (death rate 3.63/100 000),suicide (death rate 2.15/100 000),accidental poisoning (death rate 1.42/100 000) and asphyxiation (death rate 0.89/100 000).The leading cause of injury deaths among residents of different genders and different ages was transportation accidents.The death rate of unintentional falls increased at an average annual rate of 8.4% (APC=8.37%,P<0.001),while the death rates of transportation accidents (APC=-5.93%,P<0.001) and accidental poisoning (APC=-16.61%,P<0.001) showed decreasing trend. Conclusion The accidental injury mortality rate of Jiaozuo residents displays a decreasing trend,transportation accident is the first cause of injury death,while unintentional fall is the fastest rising cause of injury death.The main cause of death is different in different groups,and targeted measures should be taken to prevent injury according to different causes of injury death.