Objective To understand the epidemiological characteristics of influenza-like illness (ILI) and the patterns of prevalent strains in Xinyang from 2014 to 2024,in order to provide scientific basis for the prevention and control of influenza.Methods The data of ILI surveillance and laboratory test in the surveillance years from 2014 to 2024 in Xinyang were collected from the National Influenza Surveillance Network,and descriptive epidemiological method was used to analyze the epidemic characteristics.Results A total of 87 642 ILI cases were reported from 2014 to 2024,accounting for 1.79% of all visiting patients,proportions of ILI cases among all patients (ILI%) ranged from 0.50% to 6.40% in different years.The proportion of all ILI cases was highest in age group 0-4 years (33.99%),and was lowest in the people aged 60 years old and above (9.80%).Among 7 705 ILI samples,1 489 samples were positive for influenza nucleic acid,the positive rate was 19.33%(1 489/7 705),with the positive rates of type A,type B and mixed types of influenza virus were 11.97%(922/7 705),7.31%(563/7 705),0.05%(4/7 705),respectively.The top three surveillance years with the highest influenza nucleic acid positive rates were 2017-2018 (30.48%),2021-2022 (29.67%) and 2023-2024 (26.49%),respectively.In different surveillance years,the positive rate of influenza nucleic acid was different (χ²=405.465,P<0.001),and the influenza A and B virus typing was different (χ²=720.477,P<0.001).The positive rate of influenza nucleic acid was different among different age groups (χ²=212.207,P<0.001),and the positive rate was highest in the 5-14 years old group (27.39%),while was lowest in the 0-4 years old group (11.45%).The difference in influenza virus typing among different age groups was statistically significant (χ²=17.322,P=0.002),and influenza A virus was the dominant strain in all age groups.The dominant strains of influenza were different in different surveillance years,with influenza A virus was the dominant strain,and the peak of the pandemic occurred from the 48th week of the current year to the 4th week of the following year.Conclusion Influenza was prevalent mainly in winter and spring from 2014 to 2024 in Xinyang,with alternating mixed prevalence of different influenza virus types.Influenza A strain is the epidemic dominant strain.The age group of 5-14 years is the key population for prevention and control.