Objective To study the pathogens and distribution characteristics of hand-foot-mouth disease (HFMD) in Suzhou city in 2014, and provide scientific evidence for making effective measures. Methods The Real-time RT-PCR method was applied for Enterovirus 71 and Coxasckievirus A16 Nucleic acid detection. Results 185 cases of the 343 clinically diagnosed cases were positive. Positive rate was 59.2%. Of them, there were 45 cases infected with Enterovirus 71 and 98 cases infected with Coxasckievirus A16, with positive rate of 13.1% and 28.6%, respectively. The sex ratio was 1.8:1, and the positive rate of male and female was 54.6% and 52.8%, respectively. Conclusion CoxA16 was the major pathogens causing HFMD in Suzhou in 2014, accompanied by EV71 and other intestinal virus.There was no significant difference(χ2=0.113,P>0.05) in detection rate between male and female, however, the difference was significantly(χ2=16.417,P<0.05) among counties.
Key words
Hand-foot and mouth disease /
Enterovirus /
Etiology monitoring
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] Li L, He Y, Yang H, et al. Genetic characteristics of humanenterovirus 71 and Coxsackievirus A16 circulating from 1999 to 2004 in Shenzhen, People's Republic of China[J].J Clin Microbiol,2005,43(8):3835-3839.
[2] 刘婧媛.2013年辽阳市手足口病实验室检测结果解析[J].中国保健营养,2014.05(上):2441-2442.
[3] Zhang Y, Tan XJ, Wang H, et al. An outbreak of hand,foot, and mouth disease associated with subgenotype C4of human enterovirus 71 in Shandong, China[J]. J ClinVirol,2009,44(4):262-267.
[4] 张立新.锦州市2014 年手足口病监测结果分析[J].生物技术世界,2015,(1):90.
[5] 苏晓霁.合肥地区儿童手足口病的病原学检测分析[J].医学信息,2014,27(9上):242.
[6] 张玲,魏永,胡雪影,等.宿州市2012年手足口病病原检测结果分析[J].安徽预防医学杂志,2013,19(3):219-220.
[7] 张玲.宿州市295例手足口病病原学监测结果分析[J].中国农村卫生事业管理,2014,36(4):700-702.
[8] 刘佳.2013年克拉玛依市手足口病实验室检测病原学分析[J].医学信息,2014,27(4下):129.
[9] 顾红岩,詹永婧,李辉.2013 年北京地区手足口病的流行趋势[J].中华实验和临床感染病杂,2014,8(6):768-773.
[10] 邱惠芳,潘丽峰,汤琰.上海市浦东新区2013年手足口病检测结果分析[J].中国初级卫生保健2014,28(9):97-99.
PDF(794 KB)
