Objective To understand the microbial contamination of foods in Chizhou city,and provide scientific basis for food borne diseases prevention and control. Methods The food samples were collected and detected according to the GB standard. Results A total of 215 food samples were tested, and 29 strains of pathogenic bacteria were detected with positive rate of 13.49%. The positive rate of diarrheagenic escherichia coli was 19.57%, staphylococcus aureus was 6.11%, listeria monocytogenes was 4.32%, Salmonella was 1.40% and Vibrio parahaemolyticus was 0. The detection rate of pathogenic bacteria in takeaway delivery was 45.45％, in student meal was 20.83％, in uncooked pork account and chichen was 16.67％, and in prepared meat products was 6.67%. Food borne bacteria were not detected in cooked and prefabricated animal aquatic products, nuts and seeds of mud, and condiment. The detection rate of pathogenic bacteria in packaged and unpacked foods were 0 and 19.46% respectively, and the difference was significantly(χ²=14.85, P＜0.01). Conclusion It was contaminated by food borne pathogens in foodstuff, which were consumed by Chizhou inhabitants.Takeout and student meal as the ready-to-eat food are at higher risks for causing food borne diseases.