Objective To understand the lenticular opacity of radiation workers. Methods Investigating the lenticular opacity of 415 radiation workers from different medical institutions and 762 non-radiation workers, analyzing the relationship of lenticular opacity with ionizing radiation, radiation workers' age, gender, radiation-exposed working period, type of work and work unit. Results The lenticular opacity of radiation workers was associated with ionizing radiation. Compared with the control group, there was statistically significant difference (χ² = 72.675, P< 0.01). The lenticular opacity was associated with age, and with the increase of age, relative risk for turbidity was 11.99. There was no difference in lenticular opacity between genders. However, the lenticular opacity was related with radiation-exposed working period, type of work and work unit, and the differences were all statistically (χ²=14.029, P＜0.01; χ²=14.457, P＜0.01; χ²=18.615, P＜0.01). Conclusion Ionizing radiation can cause lenticular opacity, and the detection rate of turbidity increased with of working age. The detection rate of interventional radiology staff was the highest.