Objective To understand the awareness level of the core information about chronic disease prevention and control among urban residents in Anqing city,so as to provide basis for health education of chronic disease. Methods Using random sampling method, the permanent resident population aged 15-69 years old from 1 440 residents of 4 regions were investigated with questionnaire. Results Awareness rate of knowledge about prevalence of chronic disease was 23.1%, salt intake was 74.5%, normal BMI was 62.1%. There was statistically significant difference in awareness rate among four districts (P<0.01). Conclusion The distribution of awareness rate of core information about chronic disease prevention and control was imbalance among different people groups and areas. The health education about chronic disease should be carried out.