Objective To understand the etiology and distribution of hand foot mouth disease (HFMD) in Dangshan county from 2015 to 2017. Methods A total of 180 samples of throat swabs were collected from People's Hospital of Dangshan County from 2015-2017. Fluorescent quantitative PCR (RT-PCR) was used to detect enterovirus 71 (EV71), coxsackievirus A16 (CoxA16) and intestinal universal nucleic acid. Results Of the 180 clinical specimens of HFMD, 82 were positive for enterovirus nucleic acid, with a positive rate of 45.56%. From 2015 to 2017, the positive rate of enterovirus was 46.67%, 38.33% and 51.67%, respectively. There was no significant difference in the positive rate of each year(χ2=2.195. P=0.334). There were 18 cases of EV71 positive, 12 CoxA16 positive and 52 other enterovirus, accounting for 21.95%, 14.64%, 63.42% respectively. The positive rates of male and female were 46.96% (54/115) and 43.07% (28/65), respectively. Conclusion From 2015 to 2017, the main epidemic pathogens of HFMD in Dangshan county were not changed, and other enteroviruses were the dominant pathogens in three years, accompanied by EV71 and CoxA16.
Key words
Hand-foot-mouth disease /
Etiology Detect /
Enterovirus
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References
[1] 钱程,马焰,顾敏华,等. 2011-2014年江阴市手足口病流行病学及病原学特征[J]. 职业与健康,2015,12,31(24):3464-3466.
[2] 王利花,李军. 手足口病的流行病学及病原学研究进展[J]. 中国卫生事业管理,2010,6:419-421.
[3] 叶文,陈静芳,张如胜,等.2010-2012年长沙市手足口病病原学监测结果分析[J].中国预防医学杂志,2014,15(5):482-486.
[4] 王春荣 .多种肠道病毒在手足口病流行中扮演的角色及演变趋势[J].世界华人消化杂志,2016,24(29):4029-4039.
[5] 杨志宏,朱启镕,李秀珠,等.2002年上海手足口病病例中肠道病毒71型和柯萨奇病毒A组16型的调查[J].中华儿科杂志,2005,43(9):648-648.
[6] 郭国侠,李国兰,孟昭倩.阜阳市2011-2012年手足口病病原学检测结果分析[J]. 安徽预防医学杂志,2013,19(4):302.
[7] 张玲,魏永,胡雪影,等.宿州市2012年手足口病病原检测结果分析[J].安徽预防医学杂志,2013,19(3):219-220.
[8] 张玲,葛明明.宿州市2014年343例手足口病病原学监测结果分析[J].安徽预防医学杂志,2016,22(1):4-6.
[9] 张玲,葛明明.宿州市2012～2015年手足口病病原学检测结果及流行病学分析[J].热带病与寄生虫学,2017,15(3):139.
[10] 许泽辉,罗世强,王敬仁,等.柳州市2014年手足口病检测结果分析[J].分子诊断与治疗杂志,2015,7(6):401-405.
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