Objective To identify the prevalence and correlates of menopausal symptoms among rural women aged 40-60 in Anhui Province,China. Methods A stratified cluster sampling method was used to select 1780 rural women aged 40-60 in Anhui Province and conduted a face-to-face questionnaire survey.The Kupperman Rating Scale was used to evaluate, grade and judge the menopausal symptoms. Results There were 1780 rural women aged 40-60 participated in this study, with mean age of (50.0±5.6) years old.Among women who finished the Kupperman Scale,1004 (56.4%) reported suffering with menopausal symptoms, among which, 583 (32.8%) had mild symptoms, 357 (20.1%) had moderate symptoms, and 64 (3.6%) had severe symptoms.The main symptoms were muscle/joint pain,mood swings, vertigo, insomnia, headaches and fatigue (all over 45%).The univariate analysis showed that the prevalence of menopausal symptoms was associated with age, education background and other factors (P<0.05).Multi-variate Logistic regression analysis showed that the prevalence of menopausal symptoms was associated with age, daily work, BMI, sleep, teeth, vision, hearing, leg and foot, appetite, chronic diseases, anxiety and depression (P<0.05). Conclusion This study showed that the prevalence of menopausal symptoms was high among rural women aged 40-60 years old in Anhui Province.The possible risk factors include age, daily work, BMI, sleep, teeth, vision, hearing, leg and foot, appetite, chronic diseases, anxiety and depression.